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Autor:
Christopher F. Basler, Priya Luthra, Chad E. Mire, Hideki Ebihara, Parameshwaran Ramanan, Gaya K. Amarasinghe, Daisy W. Leung, Yoshimi Tsuda, Carla Weisend, Benjamin Yen, Gai Liu, Thomas W. Geisbert
Publikováno v:
Cell Host & Microbe. 14(1):74-84
SummaryThe cytoplasmic pattern recognition receptor RIG-I is activated by viral RNA and induces type I IFN responses to control viral replication. The cellular dsRNA binding protein PACT can also activate RIG-I. To counteract innate antiviral respons