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pro vyhledávání: ''
Autor:
Wen-Jie Luo, Dingwei Ye, Yongqiang Huang, Yuan-Yuan Qu, Wenhao Xu, Mengfei Yao, Jun Wang, Chunguang Ma, Yiping Zhu, Hailiang Zhang, Fangning Wan
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and development in bladder cancer. However, the underlying molecular mechanisms remain elusive. We previously identified a novel lncRNA signature related to immunity and prog
Autor:
Ben Liu, Yufan Ying, Xueyou Ma, Xiao Wang, Xiangyi Zheng, Weiyu Wang, Liping Xie, Bo Xie, Haiyun Xie, Jiangfeng Li, Jian Wu, Jiajie Fang, Shiming Chen
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Emerging discoveries of dynamic and reversible N6-methyladenosine (m6A) modification on RNA in mammals have revealed the key roles of the modification in human tumorigenesis. As known m6A readers, insulin-like growth factor 2 mRNA-binding proteins (I
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-9 (2021)
Cell Death & Disease
Cell Death & Disease
MicroRNA (miR)-361-5p has been studied to suppress gliomas development. Based on that, an insight into the regulatory mechanism of miR-361-5p in gliomas was supplemented from ubiquitin protein ligase E3 component N-recognin 5 (UBR5)-mediated ubiquiti
Autor:
Giorgio Durante, Cosimo Misciali, Martina Lambertini, Cristian Bassi, Massimo Negrini, Elisa Porcellini, Eric Londin, Mattia Riefolo, Isidore Rigoutsos, Roberta Roncarati, Phillipe Loher, Emi Dika, Annalisa Patrizi, Manuela Ferracin, Elisabetta Broseghini
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
Malignant cutaneous melanoma (CM) is a potentially lethal form of skin cancer whose worldwide incidence has been constantly increasing over the past decades. During their lifetime, about 8% of CM patients will develop multiple primary melanomas (MPMs
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
Nuclear factor erythroid 2-related factor 2 (Nrf2, also called NFE2L2) plays an important role in cancer chemoresistance. However, little is known about the role of Nrf2 in tumor mutation burden and the effect of Nrf2 in modulating DNA mismatch repai
Autor:
Muwen Wang, Zilian Cui, Peng Sun, Qiang Wang, Hanbo Wang, Yun Dai, Dong Zhang, Jin Wang, Weiting Kang, Taiguo Qi, Xunbo Jin
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-16 (2020)
Cell Death & Disease
Cell Death & Disease
Apart from being potential prognostic biomarkers and therapeutic targets, long non-coding RNAs (lncRNAs) modulate the development and progression of multiple cancers. PlncRNA-1 is a newly discovered lncRNA that exhibits the above properties through m
Autor:
Hongyi Zhu, Jie Zhang, Huojian Shen, Yuanwen Chen, Zhi-Yong Shen, Hua Liu, Changlin Qian, W. Qiu, Jian-Hua Sun
Publikováno v:
Cell Death and Disease, Vol 11, Iss 9, Pp 1-15 (2020)
Cell Death & Disease
Cell Death & Disease
Gastric cancer (GC) is one of the most leading malignancies. Long noncoding RNA is related to GC. In this study, 11 miRNAs in the exosomes and six lncRNAs in the tissues was examined by qRT-PCR. Correlation analysis was used to analyze the relationsh
Publikováno v:
Cell Death and Disease, Vol 11, Iss 8, Pp 1-16 (2020)
Cell Death & Disease
Cell Death & Disease
Farnesoid X receptor (FXR, encoded by NR1H4), a critical regulator of bile acid homeostasis, is widely implicated in human tumorigenesis. However, the functional role of FXR in colorectal cancer (CRC) and the precise molecular mechanism remain unclea
Autor:
Jiuling Cheng, Shanshan Chen, Ping Li, Hao Yang, Fangfang Li, Guojun Zhang, Guangying Cui, Tiandong Kong, Lu Chen
Publikováno v:
Cell Death and Disease, Vol 11, Iss 8, Pp 1-16 (2020)
Cell Death & Disease
Cell Death & Disease
Phosphoglycerate mutase 1 (PGAM1) is a recently identified key catalytic enzyme in aerobic glycolysis. Recent literature has documented that dysregulated PGAM1 expression is associated with tumorigenesis in various cancers. However, the expression st
Publikováno v:
Cell Death and Disease, Vol 11, Iss 7, Pp 1-12 (2020)
Cell Death & Disease
Cell Death & Disease
Circular RNAs (circRNAs) are an emerging class of non-coding RNAs, identified to participate in multiple malignancies. Nevertheless, the clinical significance, biological function, and regulatory mechanisms of circRNAs in colon cancer (CC) remain lar