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Autor:
Li Fu, Huikun Zhang, Xiaoli Liu, Yawen Zhao, Zhifang Guo, Ming Zhang, Feng Gu, Yongjie Ma, Yongzi Chen
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-17 (2021)
Cell Death and Disease, Vol 12, Iss 10, Pp 1-17 (2021)
Breast cancer is the most common type of cancer worldwide. However, the well-known molecular biomarkers are not enough to meet the needs of precision medicine. In search for novel targets in this regard, we reported ITSN1 (intersectin1) as one of the
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 6, Pp 1-14 (2021)
Cell Death and Disease, Vol 12, Iss 6, Pp 1-14 (2021)
In eukaryotes, histones and their variants are essential for chromatin structure and function; both play important roles in the regulation of gene transcription, as well as the development of tumors. We aimed to explore the genomics data of hepatocel
Autor:
Shuai Zong, Xin Liu, Xiaotian Yuan, Laicheng Wang, Yueran Zhao, Wenli Mu, Ping Li, Yu Xia, Yunyun Qu, Huanxin Sun, Yulian Jiao, Xiaowen Liu, Bin Cui, Shuang Liu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
FKBP4 belongs to the family of immunophilins, which serve as a regulator for steroid receptor activity. Thus, FKBP4 has been recognized to play a critical role in several hormone-dependent cancers, including breast and prostate cancer. However, there
Autor:
Yunlong Jia, Wei Lv, Tianxu Liu, Yuqing Duan, Jing Qin, Lihua Liu, Meixiang Sang, Jiali Wang, Zishuo Cheng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Long noncoding RNAs (lncRNAs) emerge as essential roles in the regulation of alternative splicing (AS) in various malignancies. Serine- and arginine-rich splicing factor 1 (SRSF1)-mediated AS events are the most important molecular hallmarks in cance
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
The molecule mechanisms of long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) in human diseases have been broadly studied recently, therefore, our research aimed to assess the effect of lncRNA taurine upregulated gene 1 (TUG1)/miR-187-3p/tescalcin
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Grainyhead-like 1 (GRHL1) is a transcription factor involved in embryonic development. However, little is known about the biological functions of GRHL1 in cancer. In this study, we found that GRHL1 was upregulated in non-small cell lung cancer (NSCLC
Autor:
Fei Zhang, Zhaosong Wang, Yuying Zhu, Zicong Gao, Ruifang Niu, Zhiyong Wang, Xingxing Han, He Zhang, Yanfen Cui, Ran Tian
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 5, Pp 1-18 (2021)
Cell Death and Disease, Vol 12, Iss 5, Pp 1-18 (2021)
Background: The failure of chemotherapy is accompanied by the emergence of drug resistance and tumor relapse. Tumor metastasis induced by drug resistance is a major challenge in successful cancer treatment. Nevertheless, the mechanisms underlying the
Autor:
Tae Hyun Yoo, Gyuri Kim, Seonghun Kim, Shin Wook Kang, Jeongho Joo, Huiyoon Shin, Bo Young Nam, Jung Tak Park, Jimin Park, Pureunchowon Lee, Seung Hyeok Han
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-1 (2021)
Cell Death and Disease, Vol 12, Iss 4, Pp 1-1 (2021)
Kidney tubular cell death induced by transforming growth factor-β1 (TGF-β1) is known to contribute to diabetic nephropathy, a major complication of diabetes. Caspase-3-dependent apoptosis and caspase-1-dependent pyroptosis are also involved in tubu
Autor:
Anqi Xu, Cheng Xie, Xizhao Wang, Renhui Yi, Yu Zeng, Jie Lin, Mingfeng Zhou, Tengyue Huang, Jie Luo, Ye Song, Zhiyong Wu, Shengfeng Ding
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
The homeobox protein cut-like 1 (CUX1) comprises three isoforms and has been shown to be involved in the development of various types of malignancies. However, the expression and role of the CUX1 isoforms in glioma remain unclear. Herein, we first id
Autor:
Juan Elías González-Correa, Per Anderson, Virgínea de Araújo Farias, Sofía T. Menéndez, M. Victoria Gonzalez, Juan Esteban Quintero, Sabina Sánchez-Hernández, Turid Hellevik, Juan Carlos Rodríguez-Manzaneque, Verónica Blanco-Lorenzo, Inigo Martinez-Zubiaurre, Federico Zurita, Eva Allonca, Nadina Erill-Sagalés, Rene Rodriguez, Francisco Martin, Pilar M. Muñoz, Ana Belén Carrillo-Gálvez
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-12 (2020)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
WOS:000595630900001
RUO. Repositorio Institucional de la Universidad de Oviedo
Cell Death & Disease
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
WOS:000595630900001
RUO. Repositorio Institucional de la Universidad de Oviedo
Cell Death & Disease
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Sarcomas are mesenchymal cancers with poor prognosis, representing about 20% of all solid malignancies in children, adolescents, and young adults. Radio- and chemoresistance are common features of sarcomas warranting the search for novel prognostic a