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pro vyhledávání: '"Rajeeb K. Swain"'
Publikováno v:
Cell Communication and Signaling : CCS
Background Activation of the Wnt signalling cascade is primarily based on the interplay between Wnt ligands, their receptors and extracellular modulators. One prominent family of extracellular modulators is represented by the SFRP (secreted Frizzled-
Publikováno v:
Cell Communication and Signaling, Vol 3, Iss 1, p 12 (2005)
Cell communication and signaling : CCS
Cell communication and signaling : CCS
Background S ecreted F rizzled r elated p roteins (SFRPs) are extracellular regulators of Wnt signaling. These proteins contain an N-terminal cysteine rich domain (CRD) highly similar to the CRDs of the Frizzled family of seven-transmembrane proteins