Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Melanie Boerries"'
Autor:
Eyleen Corrales, Ella Levit-Zerdoun, Patrick Metzger, Ralf Mertes, Ariane Lehmann, Julia Münch, Steffen Lemke, Silke Kowar, Melanie Boerries
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Current therapeutic management of advanced melanoma patients largely depends on their BRAF mutation status. However, the vast heterogeneity of the tumors hampers the success of therapies targeting the MAPK/ERK pathway alone. Disse
Externí odkaz:
https://doaj.org/article/9a5a8d5277504e11882ad210e91ce9a0
Autor:
Eyleen Corrales, Ella Levit-Zerdoun, Patrick Metzger, Silke Kowar, Manching Ku, Tilman Brummer, Melanie Boerries
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-22 (2021)
Abstract Background Vemurafenib (PLX4032) is one of the most frequently used treatments for late-stage melanoma patients with the BRAF V600E mutation; however, acquired resistance to the drug poses as a major challenge. It remains to be determined wh
Externí odkaz:
https://doaj.org/article/866ef96ae5834d83bcaada44126bbf7c