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Autor:
Ya-Hui Dong, Peile Ren, Shafiu Adam Umar, Yiwei Zhao, Qiufang Li, Yong-Mei Nie, Fengxu Yu, Tan Yang
Publikováno v:
Cell Biochemistry and Biophysics
Atherosclerosis is a significant cause of mortality and morbidity. Studies suggest that the chemokine receptor CX3CR1 plays a critical role in atherogenesis. Shear stress is an important mechanical force that affects blood vessel function. In this st
Publikováno v:
Cell Biochemistry and Biophysics
Appropriate mechanical forces on cells are vital for normal cell behaviour and this review discusses the possibility that tumour initiation depends partly on the disruption of the normal physical architecture of the extracellular matrix (ECM) around
Publikováno v:
Cell Biochemistry and Biophysics. 76:463-470
Melatonin exists as an active ingredient in several foods and has been reported to inhibit fatty liver disease in animals; however, its molecular mechanisms are not well elucidated. Herein, we explored effects of melatonin on lipid accumulation induc
Publikováno v:
Cell Biochemistry and Biophysics
Major factors leading to the development of atherosclerosis are a high cholesterol (Chol) level in the blood and oxidative stress. Both promote the formation of Chol microcrystals in blood vessel walls. Deposition of Chol microcrystals in arterial in
Autor:
V. Shanthi, K. Rohini
Publikováno v:
Cell Biochemistry and Biophysics. 76:357-376
The Influenza A virus is one of the principle causes of respiratory illness in human. The surface glycoprotein of the influenza virus, neuraminidase (NA), has a vital role in the release of new viral particle and spreads infection in the respiratory
Publikováno v:
Cell Biochemistry and Biophysics
Pathophysiology of delayed cerebral ischemia and cerebral vasospasm following aneurysmal subarachnoid hemorrhage is still poorly recognized, however free radicals are postulated as one of the crucial players. This study was designed to scrutinize whe
Autor:
Seyed Shahriar Arab, Leila Karami, Shima Aliebrahimi, Shideh Montasser Kouhsari, Seyed Nasser Ostad
Publikováno v:
Cell Biochemistry and Biophysics
c-Met receptor tyrosine kinase is a proto-oncogene whose aberrant activation is attributed to a lower rate of survival in most cancers. Natural product-derived inhibitors known as "fourth generation inhibitors" constitute more than 60% of anticancer
Autor:
Orawan Wanachewin, Kanchanit Boonmaleerat, Prachya Kongtawelert, Thanyaluck Phitak, Peraphan Pothacharoen
Publikováno v:
Cell Biochemistry and Biophysics. 76:279-292
Osteoarthritis is a degenerative joint disease in which interleukin-1β plays a major role in the inflammatory process. Administration of collagen hydrolysate was an optional treatment of osteoarthritis. Fish has become an interesting source of colla
Autor:
Ann Barry Flood, Eunice Y. Chen, Harold M. Swartz, Lesley A. Jarvis, P.E. Schaner, Periannan Kuppusamy, Huagang Hou, Sergey Petryakov, Wilson Schreiber, Benjamin B. Williams, Rose M. Caston, Maciej M. Kmiec
Publikováno v:
Cell Biochemistry and Biophysics. 75:275-283
Hypoxic tumors are more resistant to radiotherapy and chemotherapy, which decreases the efficacy of these common forms of treatment. We have been developing implantable paramagnetic particulates to measure oxygen in vivo using electron paramagnetic r
Autor:
Nivya James, K. Ramanathan
Publikováno v:
Cell Biochemistry and Biophysics. 76:111-124
Anaplastic lymphoma kinase is a tyrosine kinase receptor protein belonging to insulin receptor superfamily. Gene fusions in anaplastic lymphoma kinase are associated with non-small cell lung cancer development. Hence, they are of immense importance i