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Publikováno v:
Cell and Tissue Research. 386:585-603
The underlying mechanism of the trans-sutural distraction osteogenesis (TSDO) technique as an effective treatment that improves the symptoms of midfacial hypoplasia syndromes is not clearly understood. Increasing findings in the orthopedics field ind
Autor:
Aimilia Varela, Ioanna Kostavasili, Alexia Polissidis, Ismini Kloukina, Manolis Mavroidis, Modestos Nakos-Bimpos, Mary Tsikitis, Elsa Tsoupri, Yassemi Capetanaki, Despoina Miliou, Constantinos H. Davos, Eleni Vasilaki
Publikováno v:
Cell and Tissue Research. 385:675-696
The desmin-associated protein myospryn, encoded by the cardiomyopathy-associated gene 5 (CMYA5), is a TRIM-like protein associated to the BLOC-1 (Biogenesis of Lysosomes Related Organelles Complex 1) protein dysbindin. Human myospryn mutations are li
Publikováno v:
Cell and Tissue Research. 386:127-143
The World Health Organization has recognized that testicular function is temperature dependent. Testicular heat exposure caused by occupational factors, lifestyle, and clinical diseases can lead to different degrees of reproductive problems. The aim
Publikováno v:
Cell and Tissue Research. 385:539-555
Neuron-glia antigen 2 (NG2) proteoglycan and platelet-derived growth factor receptor beta (PDGFR-β) are widely used markers of pericytes, which are considered cells that form fibrotic scars in response to central nervous system insults. However, the
Publikováno v:
Cell and tissue research. 390(1)
Testicular dysfunction, a major contributory factor to infertility, has received a lot of attention over the recent years. Several studies have linked abnormal sperm function and morphology with an enhanced generation of reactive oxygen species (ROS)
Publikováno v:
Cell and Tissue Research. 384:87-97
Pulmonary injury occurring after thoracic radiotherapy is a main factor limiting the curative effect of radiotherapy. Robust activation of the Wnt signalling pathway induced by ionizing radiation stress plays a critical role in epithelial-mesenchymal
Autor:
Knut Dahl-Jørgensen, Shiva Reddy, Lars Krogvold, Owen Martin, Charlton Martin, Kevin Xueying Sun, Aamenah Al-Ani
Publikováno v:
Cell and Tissue Research. 384:655-674
Exposure of isolated human islets to proinflammatory cytokines leads to up-regulation of inducible nitric oxide synthase (iNOS), raised NO, and beta cell toxicity. These findings have led to increasing interest in the clinical utility of iNOS blockad
Publikováno v:
Cell and Tissue Research
SH3 and cysteine-rich protein 3 (STAC3), a small adapter protein originally identified as a core component of excitation–contraction coupling machinery, regulates the voltage-induced Ca2+ release in skeletal muscle. However, the possibility of addi
Autor:
Corey B. Hughes, George M. Mussman, Kathryn M. Thrailkill, Phil Ray, Virgilius Cornea, Robert C. Bunn, Iuliana Popescu, John L. Fowlkes
Publikováno v:
Cell and Tissue Research. 384:527-543
Inhibitors of sodium/glucose co-transporter 2 (SGLT2) are currently in clinical use for type 2 diabetes (T2D) treatment due to their anti-hyperglycemic effect exerted by the inhibition of glucose reabsorption in the kidney. Inhibition of SGLT2 is ass
Publikováno v:
Cell and Tissue Research. 384:59-72
The trochlear projection is unique among the cranial nerves in that it exits the midbrain dorsally to innervate the contralateral superior oblique muscle in all vertebrates. Trochlear as well as oculomotor motoneurons uniquely depend upon Phox2a and