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pro vyhledávání: '"Rebecca A. Haeusler"'
Autor:
Fanny Langlet, Christoph Buettner, Daniel Lindén, Kumiko S. Aizawa, Domenico Accili, Ling Wang, Rebecca A. Haeusler, Elke Ericson, Anders Johansson, Joshua R. Cook, Tyrrell Norris
Publikováno v:
Cell. 171:824-835.e18
Insulin resistance is a hallmark of diabetes and an unmet clinical need. Insulin inhibits hepatic glucose production and promotes lipogenesis by suppressing FOXO1-dependent activation of G6pase and inhibition of glucokinase, respectively. The tight c