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mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant
Autor:
Wilfredo F. Garcia-Beltran, Kerri J. St. Denis, Angelique Hoelzemer, Evan C. Lam, Adam D. Nitido, Maegan L. Sheehan, Cristhian Berrios, Onosereme Ofoman, Christina C. Chang, Blake M. Hauser, Jared Feldman, Alex L. Roederer, David J. Gregory, Mark C. Poznansky, Aaron G. Schmidt, A. John Iafrate, Vivek Naranbhai, Alejandro B. Balazs
Publikováno v:
Cell
Recent surveillance has revealed the emergence of the SARS-CoV-2 Omicron variant (BA.1/B.1.1.529) harboring up to 36 mutations in spike protein, the target of neutralizing antibodies. Given its potential to escape vaccine-induced humoral immunity, we