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pro vyhledávání: '"Harsh Wadhwa"'
Autor:
Ke Zhang, Aaron D. Gitler, J. Paul Taylor, Kai Ruan, Jonathan C. Grima, Jeffrey D. Rothstein, Peiguo Yang, Thomas E. Lloyd, Alyssa N. Coyne, Harsh Wadhwa, J. Gavin Daigle, Frank Rigo, Kathleen M. Cunningham, Kelly Bowen
Publikováno v:
Cell. 173:958-971.e17
Defects in nucleocytoplasmic transport have been identified as a key pathogenic event in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) mediated by a GGGGCC hexanucleotide repeat expansion in C9ORF72, the most common genetic ca