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pro vyhledávání: '"David L. Huso"'
Autor:
David L. Huso, David M. Feldser, Mary Armanios, Ling Yang Hao, Baktiar O. Karim, Carol W. Greider, Margaret A. Strong
Publikováno v:
Cell. 123(6)
SummaryAutosomal-dominant dyskeratosis congenita is associated with heterozygous mutations in telomerase. To examine the dosage effect of telomerase, we generated a line of mTR+/− mice on the CAST/EiJ background, which has short telomeres. Interbre
Publikováno v:
Cell. (3):331-344
Alternative splicing of the gene for Stat3, a transcription factor activated by the IL-6 family of cytokines, produces two isoforms: Stat3alpha and a dominant-negative variant, Stat3beta. Stat3beta-deficient mice were generated by gene targeting. Des