Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Patrick T. Ellinor"'
Publikováno v:
Cardiovascular Research. 109:493-501
Atrial fibrillation (AF) is the most common cardiac arrhythmia with well-established clinical and genetic risk components. Genome-wide association studies (GWAS) have identified 17 independent susceptibility signals for AF at 14 genomic regions, but
Autor:
Saagar Mahida, Marc D. Lemoine, David J. Milan, Robert W. Mills, Bridget Simonson, Nathan R. Tucker, Patrick T. Ellinor, Vincenzo Macri, Saumya Das
Publikováno v:
Cardiovascular Research. 101:326-334
Background A recent genome-wide association study identified a susceptibility locus for atrial fibrillation at the KCNN3 gene. Since the KCNN3 gene encodes for a small conductance calcium-activated potassium channel, we hypothesized that overexpressi
Publikováno v:
Cardiovascular Research. 89(4):692-700
Atrial fibrillation (AF) is the most common cardiac rhythm abnormality and represents a major burden, both to patients and to health-care systems. In recent years, increasing evidence from population-based studies has demonstrated that AF is a herita
Autor:
Huiqing Cao, Ling Zhao, Saagar Mahida, Yi Gang Li, Jie Dong, Zhijun Sun, Jian Sun, Michael L. Zhang, Xiao-Li Tian, Yi Xin Zhang, Emelia J. Benjamin, Fan Yang, Qun Shan Wang, Shuo Li, Gu Yan Zheng, Ji Fang Ma, Yan Yao, Patrick T. Ellinor, Rui Zhang, Ming Jun Feng, Xiaomin Chen
Publikováno v:
Cardiovascular research. 109(3)
Aims Atrial fibrillation (AF) is a common arrhythmia with an important heritable aspect. The genetic factors underlying AF have not been fully elucidated. Methods and results We screened six candidate genes ( CAV1 , KCNJ2 , KCNQ1 , NKX2.5 , PITX2 , a