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Autor:
Jordi Camps, Isabel Fort-Gallifa, Vicente Martín-Paredero, Anabel García-Heredia, ez-Aguilera, Anna Hérn, Jorge Joven
Publikováno v:
Cardiovascular Pharmacology: Open Access.
Background: Clopidogrel is an antiplatelet agent used in the treatment of vascular diseases. It requires in vivo bio activation linked to the cytochrome P450. Several studies reported that paraoxonase-1 (PON1) was a crucial enzyme in clopidogrel acti