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Autor:
Beibei Luo, Yun Zhang, Wen-ke Wang, Xiangjuan Liu, Bo Li, Cheng Zhang, Xiaoman Liu, Yanfei Xia, Ming-Xiang Zhang, Fengshuang An
Publikováno v:
Cardiovascular Drugs and Therapy. 28:33-43
Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is important in inflammation of several diabetic complications. However, the potential role of NLRP3 inflammasome in the inflammatory process of diabetic cardiomyo
Publikováno v:
Cardiovascular Drugs and Therapy. 23:271-280
Prolonged sympathetic activation is damaging to the heart and experimental norepinephrine (NE) infusion induces the deposition of myocardial collagen. This study investigated the effects of NE on collagen and transforming growth factor-beta1 (TGF-bet
Autor:
Paul Ernsberger, Ismail A. Dreshaj, Laura A. Collins, Lynette M. Graff, Marilyn E. Graves, Danette L. Grove, Musa A. Haxhiu, Marie O. Christen, Siegfried G. Schäfer
Publikováno v:
Cardiovascular Drugs and Therapy. 8:27-41
Sympathoadrenal inhibition by a direct action within the central nervous system is an advantageous route to blood pressure control. Stimulation of brain alpha 2-adrenergic receptors is one mechanism for sympathoadrenal suppression, but comes at the c