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Autor:
Jiasi Zhang, Yuxi Liu, Qun Li, Liping Zuo, Bo Zhang, Fei Zhao, Fengjuan Fan, Shanshan Luo, Yu Hu, Chunyan Sun
Publikováno v:
Carcinogenesis. 44:242-251
Overactive fatty acid metabolism is usually found in hematological malignancies including multiple myeloma (MM), but the underlying mechanisms remain unclear. Here, we reveal that acyl-CoA synthetase long-chain family member 4 (ACSL4) is abnormally o
Autor:
Fanghua Chen, Ling Aye, Lei Yu, Longzi Liu, Yuming Liu, Youpei Lin, Dongmei Gao, Qiang Gao, Shu Zhang
Publikováno v:
Carcinogenesis. 44:232-241
Protein tyrosine phosphatases (PTPs) are involved in malignant transformation and metastasis. According to one of our previous studies, Slingshot homolog 1 (SSH1), a member of PTPs, is significantly associated with the survival of intrahepatic cholan
Publikováno v:
Carcinogenesis. 44:252-262
Breast cancer is one of the most common and disastrous neoplasm for women worldwide, especially triple-negative breast cancer (TNBC). Emerging evidences have demonstrated that RNase subunits are closely related to the occurrence and development of ma
Publikováno v:
Carcinogenesis. 44:197-208
AT-Rich Interaction Domain 1A (ARID1A) is an important SWItch/Sucrose Non-Fermentation (SWI/SNF) chromatin remodeling complex subunit, and its coding gene has a high mutation frequency in many cancers. Current studies have reported that ARID1A mutati
Autor:
Zhihan Xiao, Mingxuan Si, Jing Cao, Xiru Chen, Zichen Wang, Tongyu Zhang, Yichan Zhou, Hai Li, Juncheng Dai, Cheng Wang, Liang Chen, Jing Xu
Publikováno v:
Carcinogenesis. 44:263-276
Despite the improvement of current classical treatment, the prognosis of esophageal squamous cell carcinoma (ESCC) remains poor. Immunotherapy, as a new treatment method, has revolutionized the therapy of various cancer types and created more attract
Publikováno v:
Carcinogenesis. 44:119-128
The crucial roles of enhancer RNAs (eRNAs) in the regulation of gene expression in human diseases have drawn wider and wider attention in recent years. However, the specific expression profile and function of eRNAs are still rarely discussed in oral
Publikováno v:
Carcinogenesis. 44:129-142
Iron metabolism plays an important role in maintaining cellular multiple biological functions. Dysfunction of iron homeostasis-maintaining systems was observed in many diseases, including cancer. Ribosomal L1 domain-containing 1 (RSL1D1) is an RNA-bi
Autor:
Mohammad Faujul Kabir, Jazmyne L Jackson, Annie D Fuller, Leonny Gathuka, Adam L Karami, Don-Gerard Conde, Alena Klochkova, Anbin Mu, Kathy Q Cai, Andres J Klein-Szanto, Amanda B Muir, Kelly A Whelan
Publikováno v:
Carcinogenesis. 44:182-195
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive forms of human malignancy, often displaying limited therapeutic response. Here, we examine the non-steroidal anti-inflammatory drug diclofenac (DCF) as a novel therapeutic agent
Autor:
Dmytro Zabolotnyi, Olena Kvasha
Publikováno v:
Carcinogenesis. 44:175-181
The aim of study is to develop a new method of connecting the dura mater (DM) defects in frontal sinus tumors with intracranial spread using high-frequency bipolar coagulation for welding of living tissues. Depending on the method of DM defect repair
Publikováno v:
Carcinogenesis; Feb2022, Vol. 43 Issue 2, p79-81, 3p