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Autor:
Michael Hoffmeister, Hermann Brenner, Kalai Selvi Shanmugam, Barbara Burwinkel, Jenny Chang-Claude
Publikováno v:
Carcinogenesis. 28:1914-1917
The Wnt-beta-catenin pathway plays a central role in colorectal tumorigenesis. Frizzled-related protein (FRZB, also termed secreted frizzled-related protein 3, sFRP3) antagonizes the signaling of wingless (Wnt) ligands through the frizzled membrane-b