Zobrazeno 31 - 40
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Autor:
Woon-Puay Koh, David Van Den Berg, Renwei Wang, Heather H. Nelson, Mimi C. Yu, Aizhen Jin, Jian-Min Yuan
Publikováno v:
Carcinogenesis. 32:1507-1511
Cigarette smoking is a risk factor for colorectal cancer. Putative colorectal procarcinogens in tobacco smoke include polycyclic aromatic hydrocarbons and heterocyclic aromatic amines that are known substrates of glutathione S-transferases (GSTs). Th
Autor:
Maria Teresa Landi, Yufei Wang, Demetrius Albanes, Patrick Sulem, Kari Stefansson, Michael J. Thun, Margaret R. Spitz, Jiangong Niu, Hui Zhao, Qingyi Wei, Sheng Wei, Li-E Wang, Richard S. Houlston, Zhensheng Liu, Thorunn Rafnar, Paul Brennan, Neil E. Caporaso, Christopher I. Amos, Younghun Han, James McKay, Wei V. Chen
Publikováno v:
Carcinogenesis. 32:507-515
Published genome-wide association studies (GWASs) have identified few variants in the known biological pathways involved in lung cancer etiology. To mine the possibly hidden causal single nucleotide polymorphisms (SNPs), we explored all SNPs in the e
Autor:
Ming Chang Shen, Asif Rashid, Jia Rong Cheng, Gabriella Andreotti, Hong Li Xu, Kai Yu, Lisa W. Chu, Bing Sheng Wang, Yu Tang Gao, Ann W. Hsing
Publikováno v:
Carcinogenesis. 32:58-62
Biliary tract cancers are rare but fatal malignancies, with increasing incidence in Shanghai, China. Gallstones, the primary risk factor for biliary tract cancer, typically result from oversaturation of cholesterol in bile. We examined the associatio
Autor:
Kishore Guda, Stephan M. Tanner, Sandya Liyanarachchi, Albert de la Chapelle, Heather Hampel, Leanna Natale, Sanford D. Markowitz, Jerneja Tomsic
Publikováno v:
Carcinogenesis
The genetic component of colorectal cancer (CRC) predisposition has been only partially explained. We recently suggested that a subtle decrease in the expression of one allele of the TGFBR1 gene was a heritable quantitative trait predisposing to CRC.
Autor:
Zhibin Hu, Shiyang Pan, Hongxia Ma, Jing Dong, Wenping Chen, Mingfeng Zhang, Yongqian Shu, Lin Xu, Guangfu Jin, Yi Wang, Juncheng Dai, Hongbing Shen
Publikováno v:
Carcinogenesis. 31:1080-1086
Over the last decades, combined chemotherapies that inhibit different signalling pathways together have been demonstrated to be more effective to treat the non-small-cell lung cancer (NSCLC). The epidermal growth factor receptor (EGFR) and the vascul
Autor:
Shizuka, Sasazuki, Manami, Inoue, Norie, Sawada, Motoki, Iwasaki, Taichi, Shimazu, Taiki, Yamaji, Shoichiro, Tsugane, H, Shimizu
Publikováno v:
Carcinogenesis. 31:712-718
Gastric carcinogenesis may be under the combined influence of factors related to the host, Helicobacter pylori bacterial virulence and the environment. One possible host-related factor is the inflammatory or immune response. To clarify this point, we
Autor:
Chiu-Chen Tseng, Kimberly D. Siegmund, Wendy Cozen, Anna H. Wu, Peggy Wan, Darryl Shibata, Peter W. Laird, Tiffany I. Long
Publikováno v:
Carcinogenesis. 31:1060-1067
Observationalepidemiologicalstudiesandrandomizedtrialshavereported a protective effect of estrogen and progestin therapy(EPT) on the risk of colorectal cancer but the findings onestrogen-alone therapy (ET) are less consistent. The mechanismby which
Autor:
Alexander W. Daudt, Elena Matos, José Eduardo Levi, Ana M. B. Menezes, Stephanie Villar, Michael Pawlita, Victor Wünsch-Filho, Sergio Koifman, Katarzyna Szymańska, Maria Paula Curado, Paolo Boffetta, Paul Brennan, Tim Waterboer, Pierre Hainaut, José Eluf-Neto
Publikováno v:
Carcinogenesis. 31:1054-1059
Cancers of the upper aerodigestive tract [(UADT): oral cavity, pharynx, larynx and oesophagus] have high incidence rates in some parts of South America. Alterations in the TP53 gene are common in these cancers. In our study, we have estimated the pre
Autor:
Lindsay M. Morton, Tongzhang Zheng, James R. Cerhan, Sophia S. Wang, Mark P. Purdue, Idan Menashe, Bruce K. Armstrong, Richard K. Severson, Anne Kricker, Yawei Zhang, Stephen J. Chanock, Kevin B. Jacobs, Nathaniel Rothman, Wendy Cozen, Patricia Hartge, Scott Davis, Meredith Yeager, Qing Lan, Nilanjan Chatterjee, Claire M. Vajdic, Andrew E. Grulich, Theodore R. Holford, Brian P. Leaderer
Publikováno v:
Carcinogenesis. 30:275-281
Toll-like receptors (TLRs) may influence the development of non-Hodgkin lymphoma (NHL) given their important roles in recognizing microbial pathogens and stimulating multiple immune pathways. We conducted an investigation of TLR gene variants in a po
Publikováno v:
Carcinogenesis. 29:2112-2119
In this population-based case-control study with 325 Caucasian renal cell carcinoma (RCC) patients and 335 controls matched to cases by age, gender and county of residence, we evaluated the associations between 13 potential functional polymorphisms i