Zobrazeno 1 - 10
of 12
pro vyhledávání: ''
Autor:
Hitoshi Nakagama, Yukari Totsuka, Shigeru Marubashi, Atsushi Ochiai, Masahiko Watanabe, Katsuya Tsuchihara, Sachiyo Mimaki, Shoji Nakamori, Shogo Tanaka, Tatsuhiro Shibata, Shigekazu Takemura, Shoji Kubo, Riu Yamashita, Hiroshi Haeno, Masahiko Kinoshita
Publikováno v:
Carcinogenesis. 41:368-376
Recently identified occupational cholangiocarcinoma among printing workers is characterized by chronic bile duct injuries and precancerous or early cancerous lesions at multiple sites of the bile ducts. These observations suggested the potential mult
Autor:
Ye Xu, Yang Feng, Renjie Wang, Shaobo Mo, Guoxiang Cai, Qingguo Li, Wenqiang Xiang, Weixing Dai
Publikováno v:
Carcinogenesis. 39:1235-1244
The purpose of our study was to develop a multigene signature based on transcriptome profiles of both mRNAs and lncRNAs to identify a group of patients who are at high risk of early relapse in stages II-III colon cancer. Firstly, propensity score mat
Autor:
Maria Christina Tsourlakis, Ronald Simon, Martina Kluth, Andrea Hinsch, Andreas M. Luebke, Guido Sauter, Sarah Minner, Hans Heinzer, Cosima Göbel, Markus Graefen, Philipp Weigand, Cornelia Schroeder, Stefan Steurer, Franziska Büscheck, Emily Friedrich, Alexander Angerer, Claudia Hube-Magg, Agapi Eleftheriadou, Frank Jacobsen, Thorsten Schlomm, Corinna Wittmer, Katharina Grupp, Waldemar Wilczak, Annegret Stender
Publikováno v:
Carcinogenesis. 38:1180-1187
FOXA1 (Fork-head box protein A1, HNF-3a) is a transcription factor involved in androgen signaling with relevance for lineage-specific gene expression of the prostate. The expression was analyzed by immunohistochemistry on a tissue microarray containi
Publikováno v:
Carcinogenesis. 38:821-826
Global DNA methylation may affect chromosome structure and genomic stability and is involved in carcinogenesis. In this study, we aimed to investigate whether methylation of pericentromeric repeat NBL2 and subtelomeric repeat D4Z4 in peripheral blood
Autor:
Motonobu Saito, Shinji Ohki, Shotaro Fujita, Hirokazu Okayama, Hisahito Endo, Hiroyuki Hanayama, Leo Yamada, Tomoyuki Momma, Kosaku Mimura, Eisei Endo, Katsuharu Saito, Aung Kyi Thar Min, Koji Kase, Tomohiro Kikuchi, Koji Kono, Mai Ashizawa, Wataru Sakamoto, Zenichiro Saze, Daisuke Ujiie
Publikováno v:
Carcinogenesis. 41(5)
Adjuvant chemotherapy is considered for patients with stage II colorectal cancer (CRC) characterized by poor prognostic clinicopathological features; however, current stratification algorithms remain inadequate for identifying high-risk patients. To
Autor:
Timothy C. Thompson, Da Tian Bau, Junfeng Xu, Jian Gu, John W. Davis, Chia Wen Tsai, Christopher J. Logothetis, Wen Shin Chang
Publikováno v:
Carcinogenesis
Mitochondria play multiple important cellular functions. The purpose of this study was to evaluate whether leukocyte mitochondrial DNA copy number (mtDNAcn) is associated with aggressive prostate cancer (PCa) in African American (AA) men. We measured
Autor:
Panagiotis K. Levis, Theodoros Rampias, Konstantinos Stravodimos, Andreas Scorilas, Anastasia Tsilimantou, Margaritis Avgeris, Maria-Alexandra Papadimitriou, Konstantina Panoutsopoulou
Publikováno v:
Carcinogenesis. 40(8)
In the era of precision oncology, bladder cancer (BlCa) is characterized by generic patient management and lack of personalized prognosis and surveillance. Herein, we have studied the clinical significance of urothelial cancer associated 1 (UCA1) lnc
Autor:
Yaqi Li, Weixing Dai, Long Zhang, Shaobo Mo, Qingguo Li, Yang Feng, Wenqiang Xiang, Guoxiang Cai
Publikováno v:
Carcinogenesis. 40(7)
We postulated that expression differences of autophagy-related genes are instrumental in stratifying the risk of early relapse after surgery and evaluating the prognosis of patients with stages I–III colon cancer. Therefore, propensity score matchi
Autor:
Masaru Noda, Suguru Hayase, Koji Kono, Shinji Ohki, Takahiro Nakajima, Seiichi Takenoshita, Hirokazu Okayama, Keita Aoto, Tomoyuki Momma, Katsuharu Saito, Shun Chida
Publikováno v:
Carcinogenesis. 37:878-887
To develop prognostic biomarkers that can discriminate stage II-III colorectal cancer patients with high risk of postoperative recurrence, we conducted a genome-wide screening of relapse-related genes utilizing multiple microarray cohorts. Among diff
Autor:
Sandra Cid, Maria-Angeles Miranda, Francisco Dominguez, Luis O. González, Belen Fernandez-Garcia, Francisco J. Vizoso, Noemi Eiro
Publikováno v:
Carcinogenesis. 37:768-776
The aim of this work was to evaluate the expression and clinical relevance of some cytokines in breast carcinomas. An immunohistochemical study using tissue arrays and specific antibodies against interleukin 1β (IL-1β), IL-6, IL-10, IL-17, interfer