Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Takahiro Ochiya"'
Autor:
Yasuhito Tanaka, Hitoshi Nakagama, Yutaka Furutani, Soichi Kojima, Takahiro Ochiya, Takashi Kato, Xian-Yang Qin, Ken Yasukawa, Keitaro Hagiwara, Ai Hironaka-Mitsuhashi, Lee Chuen Liew, Luc Gailhouste
Publikováno v:
Cancer Science
Primary hepatic tumors mainly include hepatocellular carcinoma (HCC), which is one of the most frequent causes of cancer‐related deaths worldwide. Thus far, HCC prognosis has remained extremely poor given the lack of effective treatments. Numerous
Publikováno v:
Cancer Science
Ovarian cancer is the most lethal gynecological cancer due to lack of early screening methods and acquired drug resistance. MicroRNAs (miRNAs) are effective post‐transcriptional regulators that are transferred by extracellular vesicles, such as exo
Publikováno v:
Cancer Science
Over the past few decades, siRNA and miRNA have attracted a great deal of attention from researchers and clinicians. These molecules have been extensively studied from the standpoint of developing biopharmaceuticals against various diseases, includin
Publikováno v:
Cancer Science
Extracellular vesicles (EV), known as exosomes and microvesicles, serve as versatile intercellular communication vehicles. Increasing evidence has shown that cancer cell-derived EV carry pathogenic components, such as proteins, messenger RNA (mRNA),
Autor:
Haruhiko Sugimura, Tomoki Naoe, Atsushi Ohtsu, Chieko Kai, Tatsuro Irimura, Masataka Sata, Takahiro Ochiya, Hideo Saji, Masahiro Hayashi, Ryoji Yao, Yoshihiro Hayakawa, Hiroyoshi Nishikawa, Taku Okazaki, Akira Matsuda, Masakazu Toi, Yuichi Sugiyama, Hiroyuki Seimiya, Manabu Kawada, Hideyuki Saya
Publikováno v:
Cancer Science
Non‐clinical studies are necessary at each stage of the development of oncology drugs. Many experimental cancer models have been developed to investigate carcinogenesis, cancer progression, metastasis, and other aspects in cancer biology and these
Publikováno v:
Cancer Science. 101:2087-2092
In the past several years, the importance of microRNA (miRNA) in cancer cells has been recognized. Proper control of miRNA expression is essential for maintaining a steady state of the cellular machinery. Recently, it was discovered that extracellula
Autor:
Masato Takahashi, Kazuhiro Mino, Takahiro Ochiya, Kazuaki Nakanishi, Kazuyoshi Yanagihara, Toshiya Kamiyama, Sanae Haga, Kazuo Umezawa, Michitaka Ozaki, Akihiko Kataoka, Norihiko Takahashi, Masanori Sato, Satoru Todo, Masaya Kina
Publikováno v:
Cancer science. 102(5)
Currently, patients with peritoneal dissemination of gastric cancer must accept a poor prognosis because there is no standard effective therapy. To inhibit peritoneal dissemination it is important to inhibit interactions between extracellular matrice