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pro vyhledávání: ''
Autor:
Takanori Ishida, Takanori Watanabe, Kiyoshi Takagi, Ryuichi Yoshida, Hironobu Sasano, Hiroyoshi Suzuki, Takashi Suzuki, Minako Sakurai, Yasuhiro Miki, Yoshiaki Onodera, Kazuhiro Sakamoto, Ai Sato, Akifumi Mayama
Publikováno v:
Cancer Science
Metastatic breast cancer is a highly lethal disease, and it is very important to evaluate the biomarkers associated with distant metastasis. However, molecular features of distant metastasis remain largely unknown in breast cancer. Estrogens play an
Autor:
YueGuo Li, Liu Shuye, Lei Zhang, Hua Kang, Rui Yang, Fan Zhijuan, BingBing Liu, Tian Yaqiong, Jing Wu, Tong Li
Publikováno v:
Cancer Science
Deciphering the molecular networks that discriminate organ‐confined breast cancer from metastatic breast cancer may lead to the identification of critical biomarkers for breast cancer invasion and aggressiveness. Here metabolomics, a global study o
Autor:
Y. Li, Yuhuan Gao, Xinan Cen, Shun'e Yang, Ming Yuan, Xiubin Xiao, Wei Zhang, Yalan Wang, Yuqin Song, Rong Liang, Ningju Wang, Ou Bai, Aichun Liu, Jing-Wen Wang, Huilai Zhang, Weijing Zhang, Hanyun Ren, Xiaohui He, Liping Su, Sheng Yang, Yinan Wang, Jing Jia, Xiaoling Li, Xiuhua Sun, Yu Zhao, Huizheng Bao, Shaoxuan Hu, Yuankai Shi
Publikováno v:
Cancer Science
Primary breast diffuse large B-cell lymphoma (PB-DLBCL) is a rare subtype of DLBCL with limited data on patterns of failure. This multicenter study aimed to define the optimum treatment strategy and patterns of failure for PB-DLBCL patients. We retro
Autor:
Takayuki Ueno, Taka-Aki Sato, Nobuko Kawaguchi-Sakita, Masakazu Toi, Kazuharu Shimizu, Yoshiki Mikami, Koichi Tanaka, Masahiro Kawashima, Noriko Iwamoto, Masahiro Sugimoto, Kazuya Terasawa
Publikováno v:
Cancer Sci
High-resolution matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) is an emerging application for lipid research that provides a comprehensive and detailed spatial distribution of ionized molecules. Recent lipidomic app
Autor:
Takuya Sakyu, Takashi Suzuki, Noriaki Ohuchi, Hironobu Sasano, Satoshi Inoue, Kiyoshi Takagi, Mika Watanabe, Yoshiaki Onodera, Yasuhiro Miki, Takanori Ishida, Jun Ichi Akahira
Publikováno v:
Cancer Science. 101:2670-2675
Runx2 has been proposed as one of the pivotal factors in the process of osteogenesis and metastasis in human malignancies including breast cancer, but its details have not been evaluated. Therefore, in this study, we evaluated its expression in human
Autor:
Motoki Iwasaki, Takayuki Kinoshita, Sadako Akashi-Tanaka, Nobuko Tamura, Takashi Houjoh, Takahiro Hasebe, Tatsuhiro Shibata, Chikako Shimizu, Yuko Sasajima, Nao Okada
Publikováno v:
Cancer Science. 100:1823-1833
The present study investigated fibrotic foci (FFs), the grading system for lymph vessel tumor emboli (LVTEs), and the histological characteristics of nodal metastatic tumors that were significantly associated with the outcomes of 115 patients with in
Autor:
Takashi Fujimoto, Takamichi Sato, Yoshio Miki, Kiyohiro Nishikawa, Hisaki Nagai, Masamitsu Onda, Takemitsu Nagahata, Futoshi Akiyama, Toshihiro Tanaka, Mitsuru Emi, Goi Sakamoto, Tatsuhiko Tsunoda, Fujio Kasumi, Akira Hirano, Koji Tsumagari
Publikováno v:
Cancer Science. 95:218-225
Estrogen receptor (ER) status is an essential determinant of clinical and biological behavior of human breast cancers. While ER-positive breast cancers respond well to adjuvant hormone therapy, ER-negative tumors are generally resistant. To date, no
Publikováno v:
Cancer Science. 94:508-514
No studies have ever precisely investigated the mechanism of nodal metastasis based on the histological characteristics of tumor cells in lymph vessels and lymph nodes. The purpose of this study was to investigate whether the histological characteris
Publikováno v:
Cancer Science. 94:158-165
Whether the characteristics of tumor cells in blood vessels play an important role in the tumor progression of invasive ductal carcinoma (IDC) of the breast is not known. The purpose of this study was to investigate the significance of the characteri
Publikováno v:
Cancer science. 103(2)
Triple negative breast cancer (TNBC) is a heterogeneous, aggressive cancer for which there is no effective chemotherapy or targeted therapy. We aimed to evaluate L-type amino acid transporter (LAT) 1 and CD98 expression immunohistochemically in patie