Zobrazeno 1 - 10
of 59
pro vyhledávání: ''
Autor:
Kaori Togashi, Akira Yamauchi, Hironori Kato, Nobuhiko Shinkura, Kenichi Yoshida, Kosuke Kawaguchi, Takahiro Yamada, Ryuji Okamura, Masahiro Sugimoto, Eiji Suzuki, Hironori Haga, Masae Torii, Hirofumi Suwa, Norimichi Kan, Sachiko Takahara, Yoshiaki Matsumoto, Masahiro Kawashima, Tsuyoshi Tachibana, Masakazu Toi, Yukiko Inagaki-Kawata, Hiroshi Yoshibayashi, Takashi Inamoto, Masako Kataoka, Shingo Sakata, Nobuko Kawaguchi-Sakita, Fumiaki Yotsumoto, Kazuhiko Yamagami, Yuki Kataoka, Mitsuru Tanaka, Shinji Kosugi, Masahiro Takada, Seishi Ogawa, Shigeru Tsuyuki, Tomomi Nishimura, Susumu Mashima, Noriko Senda, Yoshio Moriguchi
Publikováno v:
Cancer Science
Predicting pathogenic germline variants (PGVs) in breast cancer patients is important for selecting optimal therapeutics and implementing risk reduction strategies. However, PGV risk factors and the performance of prediction methods in the Japanese p
Autor:
Miki Nagatsuka, Seiichiro Masui, Miwako K. Homma, Yuichiro Kiko, Yoshimi Homma, Naoto Katagata, Yuko Hashimoto, Tadashi Nomizu
Publikováno v:
Cancer Science
Overexpression of the ubiquitous protein kinase, CK2α, has been reported in various human cancers. Here, we demonstrate that nuclear and nucleolar CK2α localization in invasive ductal carcinomas of the breast is a reliable predictor of poor prognos
Autor:
Mitsue Saito, May Thinzar Hlaing, Atsushi Arakawa, Emi Tokuda, Shuji Matsuoka, Ritsuko Sasaki, Yoshiya Horimoto, Shigehisa Kitano, Harumi Saeki, Katsuya Nakai, Masami Arai, Naomi Otsuji, Aiko Kurisaki-Arakawa
Publikováno v:
Cancer Science
The frequency of microsatellite instability (MSI) is reportedly extremely low in breast cancer, despite widespread clinical expectations that many patients would be responsive to immune‐checkpoint inhibitors (ICI). Considering that some triple‐ne
Autor:
Yukie Nishiyama, Yuta Ibuki, Hidetoshi Tahara, Shinsuke Sasada, Junko Tanaka, Takayuki Kadoya, Yuki Yamamoto, Ryou‐u Takahashi, Yumiko Koi, Morihito Okada, Norio Masumoto, Tomoyuki Akita, Yasuhiro Tsutani, Daisuke Ueda
Publikováno v:
Cancer Science
Emerging evidence indicates that small RNAs, including microRNAs (miRNAs) and their isoforms (isomiRs), and transfer RNA fragments (tRFs), are differently expressed in breast cancer (BC) and can be detected in blood circulation. Circulating small RNA
Autor:
Li Hu, Tianfeng Wang, Tie Fan, Jinfeng Li, Zhaoqing Fan, Ye Xu, Benyao Lin, Yuntao Xie, Tao Ouyang, Z. Fan
Publikováno v:
Cancer Science
BRCA1/2 genes are the most frequently germline mutated DNA‐repair genes, and the survival of BRCA1/2 carriers has been extensively explored in breast cancer. However, the prevalence of germline mutations in non‐BRCA1/2 DNA‐repair genes and the
Publikováno v:
Cancer science. 113(2)
Autoantibodies (AAbs) targeted tumor-associated antigens (TAAs) have the potential for early detection of breast cancer. Here, 574 early-stage breast cancer (ES-BC) patients containing 4 subtypes (Luminal A, Luminal B, HER2+, TN), 126 benign breast d
Publikováno v:
Cancer Science
Tumor necrosis factor receptor-associated factor 6 (TRAF6) has been found to be involved in carcinogenesis in multiple cancers. However, the precise role of TRAF6 in cancer has not been extensively investigated and remains largely unknown. In this st
Autor:
Siqin Gaowa, Kazuhiro Yoshida, Manabu Futamura, Hiroki Kamino, Jesse Yu Tajima, Masayuki Tsuneki, Hirofumi Arakawa, Ryutaro Mori
Publikováno v:
Cancer Science
Mitochondria‐eating protein (Mieap), encoded by a p53‐target gene, plays an important role in mitochondrial quality control (MQC). Mieap has been reported to have a critical role in tumor suppression in colorectal cancer. Here, we investigated it
Autor:
Takanori Ishida, Takanori Watanabe, Kiyoshi Takagi, Ryuichi Yoshida, Hironobu Sasano, Hiroyoshi Suzuki, Takashi Suzuki, Minako Sakurai, Yasuhiro Miki, Yoshiaki Onodera, Kazuhiro Sakamoto, Ai Sato, Akifumi Mayama
Publikováno v:
Cancer Science
Metastatic breast cancer is a highly lethal disease, and it is very important to evaluate the biomarkers associated with distant metastasis. However, molecular features of distant metastasis remain largely unknown in breast cancer. Estrogens play an
Autor:
Takaki Hiwasa, Akiko Kuwajima, Yoshihiro Nabeya, Makoto Sumazaki, Hideaki Ogata, Hideaki Shimada
Publikováno v:
Cancer Science
Because the production of tumor‐associated antibodies (TAA) is a humoral immune response in cancer patients, serum autoantibodies may be detected even in patients with early‐stage tumors. Seventeen recombinant proteins with tags in Escherichia co