Zobrazeno 1 - 10
of 128
pro vyhledávání: ''
Autor:
Koji Kato, Kiyoshi Ando, Yasuhito Terui, Tadahiko Igarashi, Dai Maruyama, Hidetsugu Kawai, Eiji Kiyohara, Kenya Nakai, Toshiki Uchida, Tomomitsu Miyagaki, Kensei Tobinai, Mamiko Sakata-Yanagimoto, Junya Kuroda, Yoshiki Tokura, Noriko Fukuhara, Jiro Fujita, Takayuki Ishikawa, Kentaro Yonekura, Tadashi Nakanishi, Kazuhito Yamamoto, Risa Matsunaga
Publikováno v:
Cancer Science
E7777 is a recombinant cytotoxic fusion protein composed of the diphtheria toxin fragments A and B and human interleukin‐2. It shares an amino acid sequence with denileukin diftitox, but has improved purity and an increased percentage of active mon
Autor:
Hsuan Chia Yang, Yu-Chuan Jack Li, Phung Anh Nguyen, Usman Iqbal, Ching-Huan Wang, Chieh-Chen Wu, Mohaimenul Islam, Tahmina Nasrin Poly
Publikováno v:
Cancer Science
Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. The relationship between levothyroxine use and cancer risk is largely underdetermined. To investigate the magnitude of the possible association between levot
Autor:
Yasue Kimura, Eiji Oki, Yoshiaki Fujimoto, Masahito Kotaka, Koji Ando, Hiroyuki Kitao, Yuji Miyamoto, Masaki Mori, Ryota Nakanishi, Shichao Qiu, Yoshihiko Maehara, Mototsugu Shimokawa, Akitaka Makiyama
Publikováno v:
Cancer Science
Trifluridine/tipiracil (FTD/TPI) is an orally administrated anticancer drug with efficacy validated for patients with metastatic colorectal cancer (mCRC) or gastric cancer. FTD, a key component of FTD/TPI, exerts antitumor effects via its incorporati
Autor:
Yoko Inaguma, Eiichi Ohtsuka, Yukiyoshi Moriuchi, Kazuho Miyashita, Masashi Mizokami, Nobuhiko Yamauchi, Tadahiko Igarashi, Koji Izutsu, Hiroshi Gomyo, Nobuko Kubota, Ryuzo Ueda, Mio Kurata, Yoshiko Inoue, Yoshiko Atsuta, Rika Sakai, Norifumi Tsukamoto, Yoko Ushijima, Kisato Nosaka, Dai Maruyama, Sachiko Suzuki, Toshiki Uchida, Shinichiro Yoshida, Ilseung Choi, Shigeru Kusumoto, Go Yamamoto, Yasuhito Tanaka, Kensuke Kojima, Satoshi Ichikawa, Hideki Tsujimura
Publikováno v:
Cancer Science
We conducted a nationwide retrospective analysis of 116 hepatitis B virus (HBV) surface antigen (HBsAg)‐positive patients with diffuse large B‐cell lymphoma (DLBCL) and 278 HBsAg‐negative patients with DLBCL, as a control cohort, who received r
Autor:
Yusuke Okuma, Yuki Nakagawa, Kazuo Kasahara, Makoto Nishio, Naoko Sueoka-Aragane, Satoshi Watanabe, Haruhiro Saito, Koichi Goto, Kenichi Chikamori, Tomohisa Kawakami
Publikováno v:
Cancer Science
IMpower132 explored the safety and efficacy of atezolizumab plus pemetrexed and platinum‐based chemotherapy as first‐line treatment for advanced non‐small‐cell lung cancer (NSCLC). Key eligibility criteria for the phase 3, open‐label, IMpow
Autor:
Hiroaki Matsumoto, Hideyasu Matsuyama, Yukimi Sakoda, Yoji Nagashima, Takahiro Sasaki, Koji Tamada, Shunsuke Goto, Jun‐ich Mori, Keishi Adachi
Publikováno v:
Cancer Science
Chimeric antigen receptor (CAR)‐T cell therapy has shown salient efficacy in cancer immunotherapy, particularly in the treatment of B cell malignancies. However, the efficacy of CAR‐T for solid tumors remains inadequate. In this study, we display
Autor:
Huyong Zheng, Ruidong Zhang, Han Zhang, Jia Fan, Ming Sun, Chunlian Fang, Xin Tian, Xueling Zheng
Publikováno v:
Cancer Science
Acute lymphoblastic leukemia (ALL) is an aggressive hematological cancer that mainly affects children. Relapse and chemoresistance result in treatment failure, underlining the need for improved therapies. BTB and CNC homology 2 (BACH2) is a lymphoid
Autor:
Patrick Hagner, Yumi Ogaki, Harumi Kato, Takaaki Chou, Sachiko Seo, Takayuki Hirose, Kiyohiko Hatake, Kazuhito Yamamoto, Toshihiko Doi, Yasuhito Terui, Hiroshi Fujimoto, Michael Pourdehnad
Publikováno v:
Cancer Science
Non‐Hodgkin lymphoma (NHL) treated with chemoimmunotherapy has limited efficacy in some patients, resulting in relapsed or refractory disease. Avadomide (CC‐122) is a novel cereblon‐binding agent that exhibits antilymphoma and immune‐modulati
Autor:
Mari Ishigami-Yuasa, Tetsuro Watabe, Hiroyuki Harada, Rina Takayama, Hiroyuki Kagechika, Kazuki Takahashi, Katarzyna A. Podyma-Inoue, Shintaro Sakakitani
Publikováno v:
Cancer Science
Metastasis is a primary reason related to the mortality of oral squamous cell carcinoma (OSCC) patients. A program called epithelial‐mesenchymal transition (EMT) has been shown to play a critical role in promoting metastasis in epithelium‐derived
Autor:
Shintaro Miyamoto, Joe Okumoto, Takeshi Masuda, Kakuhiro Yamaguchi, Hironobu Hamada, Yu Wakabayashi, Hiroshi Iwamoto, Shinichiro Ohshimo, Yoshifumi Nishimura, Shinjiro Sakamoto, Noboru Hattori, Kiyofumi Shimoji, Kazunori Fujitaka, Yasushi Horimasu, Taku Nakashima
Publikováno v:
Cancer Science
The standard treatment for locally advanced non‐small cell lung cancer (NSCLC) is chemoradiotherapy (CRT) followed by anti‐programmed cell death‐ligand 1 (anti‐PD‐L1) treatment. BIM deletion polymorphism induces the suppression of apoptosis