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pro vyhledávání: '"35"'
Autor:
Shintaro Iwama, Yutaka Fujiwara, Aya Kuchiba, Noboru Yamamoto, Naoya Yamazaki, Yuichiro Ohe, Shiro Kimbara, Ken Ohashi, Shigehisa Kitano, Hiroshi Arima
Publikováno v:
Cancer Science
Thyroid dysfunction (TD) induced by immune checkpoint inhibitors is not sufficiently understood. The purpose of this retrospective observational study was to identify risk factors and the clinical course of TD induced by nivolumab. Patients with adva
Autor:
Tatsuya Takenouchi, Jiro Uehara, Hironobu Ihn, Taiki Isei, Naoya Yamazaki, Hiroshi Uchi, Hisashi Uhara, Hideaki Tahara, Yoshio Kiyohara, Hironobu Minami, Fujio Otsuka, Yasuhiro Fujisawa, Keiji Iwatsuki, Hajime Iizuka
Publikováno v:
Cancer Science
Promising antitumor activities of nivolumab, a fully humanized IgG4 inhibitor antibody against the programmed death-1 protein, were suggested in previous phase 1 studies. The present phase 2, single-arm study (JAPIC-CTI #111681) evaluated the antitum
Autor:
Takuma Iwai, Goro Takahashi, Yasuyuki Yokoyama, Aya Yamagishi, Hayato Kan, Michihiro Koizumi, Eiji Uchida, Tatsuro Kawagoe, Masato Nakayama, Satoshi Matsumoto, Akihisa Matsuda, Shiro Kitano, Atsushi Tatsuguchi, Seiichi Shinji, Takeshi Yamada
Publikováno v:
Cancer Science
In this study, we evaluated the clinical utility of detecting KRAS mutations in circulating cell-free (ccf)DNA of metastatic colorectal cancer patients. We prospectively recruited 94 metastatic colorectal cancer patients. Circulating cell-free DNA wa