Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yong J. Lee"'
Autor:
Yong J. Lee
Publikováno v:
Cancer Research. 80:1239-1239
Ferroptosis has been reported as a unique form of cell death. However, in recent years, researchers have increasingly challenged the uniqueness of ferroptosis compared to other types of cell death. In this study, we examined whether ferroptosis share
Autor:
Yong J. Lee
Publikováno v:
Cancer Research. 79:707-707
Introduction: Several processes lead to cell death; ferroptosis, apoptosis, necrosis, and autophagy are the primary mechanisms. Each type of biological death has been believed to have a distinct biochemical and morphological fingerprint. However, eme
Autor:
Dae Hee Lee, Yong J. Lee, Se Hoon Hong, Yoo A. Jeong, Min J. Jo, Young Sun Lee, David L. Bartlett, William T. Kwon, Haroon A. Choudry
Publikováno v:
Cancer Research. 78:2321-2321
Ferroptosis is a type of programmed cell death that depends on iron and is characterized by the accumulation of lipid peroxides. In the present study, we investigated the nature of the interplay between ferroptosis and other forms of cell death such
Publikováno v:
Cancer Research. 77:5327-5327
Although proteasome inhibitors (PIs) are used as anticancer drugs to treat various cancers, their relative therapeutic efficacy on stem cells vs. bulk cancers remains unknown. Here, we show that stem cells derived from gliomas, GSCs, are up to 1,000-
Publikováno v:
Cancer Research. 76:3009-3009
Introduction: Pseudomyxoma peritonei (PMP) is an indolent malignancy characterized by excessive production of Mucin 2 (MUC2; a gel-forming secreted mucin). We have previously demonstrated mucinous tumor growth inhibition in a patient-derived murine x
Publikováno v:
Cancer Research. 74:1345-1345
Unresectable colorectal liver metastases remain major unsolved issues and more effective regimens are urgently needed. During screening synergistic drug combinations for colon cancer therapy, we identified a novel multimodality treatment for colon ca
Autor:
Xu-Wen Liu, Marcus E. Taube, Ki-Kyung Jung, Zhong Dong, Yong J. Lee, Stefanie Roshy, Bonnie F. Sloane, Rafael Fridman, Hyeong-Reh Choi Kim
Publikováno v:
Cancer research. 65(3)
Tissue inhibitors of metalloproteinases (TIMPs) inhibit matrix metalloproteinases and some members of a disintegrin and metalloproteinase domain (ADAM) family. In addition, recent studies unveiled novel functions of TIMPs in the regulation of apoptos
Publikováno v:
Cancer Research. 73:246-246
Previous studies have demonstrated that a small subset of cancer cells is capable of tumor initiation. The existence of tumor initiating cancer stem cells (CSCs) has several implications in terms of future cancer treatment and therapies. However, rec
Publikováno v:
Cancer Research. 72:3367-3367
The aim of this study was to determine the radiosensitivity of cancer stem (tumor-initiating) cells (CSC), which are known to be responsible for tumorogenicity and metastasis. We used breast cancer stem cell (CSC)-like MDA-MB231 and MDA-MB453 cell li
Publikováno v:
Cancer Research. 71:4104-4104
Previously, we demonstrated that TRAIL-induced p38 activation was responsible for the increases of Akt catalytic and invasive activity. Interestingly, TRAIL induced dramatically Akt catalytic activation in TRAIL-sensitive cells, whereas TRAIL did not