Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Martin Pichler"'
Autor:
Felix Prinz, Martin Pichler, Herbert Stöger, Christoph Trenk, Anita Kapeller, Christiane Klec
Publikováno v:
Cancer Research. 80:P1-05
Background and Aims: Triple-negative breast cancer (TNBC) is the most aggressive subtype, and is often associated with mutations in the breast cancer susceptibility protein (BRCA) genes, which are known tumor-suppressor genes involved in DNA damage r
Autor:
Antonia D'Errico, Noemi Laprovitera, Silvia Sabbioni, Mattia Riefolo, Manuela Ferracin, Elisa Porcellini, Elisabetta Broseghini, Andrea Ardizzoni, Martin Pichler, Ingrid Garajová
Publikováno v:
Cancer Research. 80:5432-5432
Background Cancer of Unknown Primary is a rare syndrome of metastatic cancers for which the primary site cannot be recognized after detailed physical examinations, blood analyses, imaging and immunohistochemical (IHC) testing. CUPs make up 3-5% of ne
Autor:
Hildegard Greinix, Alexander Deutsch, Christine Beham-Schmid, Peter Neumeister, Marco Bischof, Chenguang Wang, Heinz Sill, Anne Krogsdam, Karoline Fechter, Katharina T. Prochazka, Gerhard G. Thallinger, Marie-Therese Frisch, Martin Pichler, Julia Feichtinger, Andreas Prokesch, Stefan Hatzl, Verena Stiegelbauer, Beate Rinner, Katrin Pansy, Kerstin Wenzl
Publikováno v:
Cancer research. 77(9)
Nuclear orphan receptor NR4A1 exerts an essential tumor suppressor function in aggressive lymphomas. In this study, we investigated the hypothesized contribution of the related NR4A family member NR4A3 to lymphomagenesis. In aggressive lymphoma patie
Autor:
Pinar Kanlikilicer, Gabriel Lopez-Berestein, Rahul Mitra, Justyna Filant, Xinna Zhang, Recep Bayraktar, Cristian Rodriguez-Aguayo, Bulent Ozpolat, Cristina Ivan, Emine Bayraktar, Andreia M. Silva, Martin Pichler, Anil K. Sood, George A. Calin, Mohammed H. Rashed, Burcu Aslan
Publikováno v:
Cancer research. 76(24)
Cancer cells actively promote their tumorigenic behavior by reprogramming gene expression. Loading intraluminal vesicles with specific miRNAs and releasing them into the tumor microenvironment as exosomes is one mechanism of reprogramming whose regul
Autor:
Cristina Ivan, Meng Chen, Martin Pichler, Hui Ling, Ajay Goel, Masahisa Ohtsuka, Milan Radovich, George A. Calin, Ondrej Slaby
Publikováno v:
Cancer Research. 77:2548-2548
The clinical significance of long noncoding RNAs (lncRNAs) in colorectal cancer (CRC) remains largely unknown. We analyzed a large panel of cancer-associated lncRNAs in 483 TCGA CRC cases, and identified that H19 correlates most significantly with ov
Publikováno v:
Cancer Research. 76:1092-1092
Triple Negative Breast Cancer (TNBC) is characterized by heterogeneous disease due to its unique molecular profile, aggressiveness, distinct metastatic patterns and lack of molecular targets such as ER, PR and HER2/neu for effective targeted therapie
Autor:
Cristina Ivan, Masahisa Ohtsuka, Hui Ling, George A. Calin, Daisuke Matsushita, Martin Pichler
Publikováno v:
Cancer Research. 76:995-995
The clinical significance of long noncoding RNAs (lncRNAs), defined as transcripts longer than 200 bp that do not code for proteins, in colorectal cancer (CRC) remains largely uncharacterized. We selected 10 lncRNAs associated with CRC, analyzed thei
Publikováno v:
Cancer Research. 76:988-988
Background: Long non-coding RNAs (LINCs) are an emerging class of molecules in cancer diagnosis and prognosis. The number of LINCs exceeds the number of protein-coding genes and their role in breast cancer is largely unknown. Methods: In this study w
Autor:
Anil K. Sood, Cristian Rodriguez Aguayo, Rahul Mitra, Mohammed H. Rashed, Cristina Ivan, Mohamed F. Abd-Ellah, Gouda K. Helal, Nashwa N. Kabil, Pinar Kanlikilicer, Gabriel Lopez Berestein, Emine Bayraktar, George A. Calin, Recep Bayraktar, Martin Pichler
Publikováno v:
Cancer Research. 76:LB-169
Exosomes have emerged as an important mediator of diverse biological functions including tumor cell progression, invasion, immune escape, and cell-to-cell communication, through the release of molecules such as mRNAs, microRNAs, and proteins. Ovarian
Autor:
Hellmut Samonigg, Nadia Dandachi, Michael R. Speicher, Ellen Heitzer, Marcus Otte, Elke Stadelmeyer, Thomas Bauernhofer, Elisabeth Maritschnegg, Gerald Höfler, Martin Pichler
Publikováno v:
Cancer Research. 72:4513-4513
Currently used non-invasive diagnostic methods for monitoring patients undergoing anti-cancer treatment are limited. The applicability of diagnostic imaging is limited and lack of sensitivity and specificity of routinely used tumor markers hampers cl