Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lauren Svenson"'
Autor:
Chris Twitty, Irene Wapnir, David A. Canton, Hiroshi Nagata, Herbert Kim Lyerly, Donna Bannavong, Erika J. Crosby, Takuya Osada, Melinda L. Telli, Lauren Svenson, Erica Browning, Kellie Malloy, Chaitanya R. Acharya, Reneta Hermiz, Kaitlin Zablotsky
Publikováno v:
Cancer Research. 81:PS17-22
Interleukin-12 (IL-12) is a pro-inflammatory cytokine involved in the generation of an inflammatory tumor microenvironment and is critical in eliciting a productive anti-tumor immune response. It has been investigated as an anti-cancer therapeutic us
Autor:
Erica Browning, Anandaroop Mukhopadhyay, Jon Salazar, David A. Canton, Reneta Hermiz, Daniel T. Fisher, Lauren Svenson, Christopher G. Twitty, Joseph J. Skitzki, Jack Y. Lee, Bianca Nguyen, Mia Han, Daniel O'Connor
Publikováno v:
Cancer Research. 80:LB-396
Clinical and preclinical studies have demonstrated that plasmid IL-12 (tavokinogene telseplasmid; TAVO) delivered intratumorally via electroporation drives IFN-γ expression and recruits T cells to the tumor microenvironment, ultimately yielding dura
Autor:
Christopher G. Twitty, Erica Browning, Jon Salazar, Jack Y. Lee, Kellie Malloy, Mia Han, Lauren Svenson, Daniel S. O'Connor, David A. Canton, Chris Baker, Reneta Hermiz, Anandaroop Mukhopadhyay, Bianca Nguyen
Publikováno v:
Cancer Research. 80:LB-390
Intratumoral (IT) delivery of plasmid IL-12 (tavokinogene telseplasmid; tavo) via electroporation (EP), collectively referred as IT-tavo-EP, generates immunologically-relevant levels of localized IL-12, triggering regression of both treated and dista