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pro vyhledávání: '"35"'
Publikováno v:
Cancer Research. 80:P4-14
Introduction: Breast cancer continues to be the most common cancer diagnosed in pregnant women. Management of breast cancer in pregnant patients requires finding a fine balance between treating the pregnant patient adequately while minimizing toxicit
Autor:
Hong Liu, Jinpu Yu, Zanmei Xu, Fei Wang, Yang Li, Siyue Zhang, Bin Wang, Beibei Yang, Xuesong Li
Publikováno v:
Cancer Research. 82:P2-03
Background: With the increase in incidence rate of breast cancer, the number of young women with breast cancer (YWBC) is rapidly augmented. As YWBC have practical needs for breast conservation and fertility, they are deserved special attention. Previ
Autor:
Jinani Jayasekera, Amy Zhao
Publikováno v:
Cancer Research. 82:5941-5941
Purpose: To evaluate the impact of early detection with screening and primary prevention with risk-reducing medication to provide personalized data that will help identify women who are more likely to benefit from various interventions or combination
Autor:
Tatsuo Sugawara, Holly NGuyen, Eva Corey, Ekaterina Nevedomskaya, Oliver Politz, Dominik Mumberg, Bernard Haendler
Publikováno v:
Cancer Research. 82:651-651
Prostate cancer is mainly driven by androgen receptor (AR) signaling so that drugs directly inhibiting this pathway such as GnRH ligands and AR inhibitors are now established as mainstay treatments. Unfortunately, treatment resistance often develops
Publikováno v:
Cancer Research. 82:3815-3815
Multiple myeloma (MM) is a cancer characterized by the unchecked proliferation of antibody-secreting plasma cells (PCs), which to date remains incurable despite therapeutic advancements. The idea that deeper tumor clearance leads to better outcomes i
Autor:
Alexandra Sala, James M. Cameron, Cerys A. Jenkins, Hugh Barr, Loren Christie, Justin J. Conn, Thomas (Jeff) R. Evans, Dean A. Harris, David S. Palmer, Christopher Rinaldi, Ashton G. Theakstone, Matthew J. Baker
Publikováno v:
Cancer Research. 82:5921-5921
Pancreatic cancer is the 7th most deadly cancer worldwide with over 460,000 victims per year. In the current diagnostic pathway, carbohydrate antigen (CA) 19-9 serum test is the first method used for detection of pancreatic cancer; although, with poo
Autor:
Mark D. Minden, Jacob M. Rowe, Emmanuel Gyan, Kohmei Kubo, Nahla Hasabou, David Delgado, Wensheng He, Stanley C. Gill, Jason E. Hill, Ramon Tiu
Publikováno v:
Cancer Research. 82:CT537-CT537
Background: Patients with acute myeloid leukemia (AML) in remission are at high risk of relapse, warranting remission-prolonging therapy. Gilteritinib is the first FMS-like tyrosine kinase 3 (FLT3) inhibitor approved as monotherapy in FLT3-mutated re
Autor:
Yue Gao, Chun-Jie Liu, Hua-Yi Li, Xiao-Ming Xiong, Sjors G.j.g. In ‘t Veld, Gui-Ling Li, Jia-Hao Liu, Guang-Yao Cai, Gui-Yan Xie, Shao-Qing Zeng, Yuan Wu, Jian-Hua Chi, Qiong Zhang, Xiao-Fei Jiao, Lin-Li Shi, Wan-Rong Lu, Wei-Guo Lv, Xing-Sheng Yang, Jurgen M.j. Piek, Cornelis D de Kroon, C.a.r. Lok, Anna Supernat, Sylwia Łapińska-Szumczyk, Anna Łojkowska, Anna J. Żaczek, Jacek Jassem, Bakhos A. Tannous, Nik Sol, Edward Post, Myron G. Best, Bei-Hua Kong, Xing Xie, Ding Ma, Thomas Wurdinger, An-Yuan Guo, Qing-Lei Gao
Publikováno v:
Cancer Research. 82:LB168-LB168
Background: Morpho-physiological alternations of platelets provided a rationale to harness RNA sequencing of tumor-educated platelets (TEPs) for preoperative diagnosis of cancer. Timely, accurate, and non-invasive detection of ovarian cancer in women
Autor:
Yi-Long Wu, Yun Fan, JianYing Zhou, Li Zhang, Qing Zhou, Wei Li, ChengPing Hu, GongYan Chen, Xin Zhang, CaiCun Zhou, Carmen González Arenas, Wei Fu, Helen Wu, Tony Mok
Publikováno v:
Cancer Research. 82:CT555-CT555
Background: In the global, phase 3 KEYNOTE-042 study, pembrolizumab (pembro) significantly prolonged OS vs chemotherapy (chemo) in patients (pts) with previously untreated advanced/metastatic NSCLC with PD-L1 TPS ≥1% without EGFR/ALK alterations. A
Autor:
Byoung Chul Cho, Rosalyn A. Juergens, Ying Cheng, Gilberto de Castro, Mustafa Erman, Jessica R. Bauman, Toshiaki Takahashi, Paul Schwarzenberger, Chengxiang Li, M. Catherine Pietanza, James Chih-Hsin Yang
Publikováno v:
Cancer Research. 82:CT561-CT561
Background: Vibostolimab (MK-7684) is a humanized monoclonal antibody (mAb) that binds to the T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT), blocking the interaction between TIGIT and its ligands, CD112 and CD155. Pembrolizumab,