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Autor:
Lee J. Helman, Troy A. McEachron
Publikováno v:
Cancer Res
Over the past few years, the field of pediatric cancer has experienced a shift in momentum, and this has led to new and exciting findings that have relevance beyond pediatric malignancies. Here we present the current status of key aspects of pediatri
Autor:
Qinghua Han, Lindsey A. Barner, Lawrence D. True, Chenyi Mao, Andrew Janowczyk, Pingfu Fu, Robert Serafin, Nicholas P. Reder, Anant Madabhushi, Jonathan T. C. Liu, Can Fahrettin Koyuncu, Patrick Leo, Sarah Hawley, Weisi Xie, Hongyi Huang, Jonathan L. Wright, Gan Gao, Adam K. Glaser, Soyoung Kang, Kevin Bishop, Nadia Postupna, C. Dirk Keene, Joshua C. Vaughan
Publikováno v:
Cancer Res
Prostate cancer treatment planning is largely dependent upon examination of core-needle biopsies. The microscopic architecture of the prostate glands forms the basis for prognostic grading by pathologists. Interpretation of these convoluted three-dim
Autor:
Klaus Pantel, Isabel Heidrich, Julia Christina Stadler, Benjamin Deitert, Yassine Belloum, Laura Keller, Mark Sementsov, Christoffer Gebhardt
Publikováno v:
Cancer Research. 82:349-358
Testing peripheral blood for circulating tumor DNA (ctDNA) offers a minimally invasive opportunity to diagnose, characterize, and monitor the disease in individual cancer patients. ctDNA can reflect the actual tumor burden and specific genomic state
Autor:
David James Britton, Pedro R. Cutillas, Vinothini Rajeeve, Nigel Heaton, Shirin Elizabeth Khorsandi, Megan S. Illingworth, Arran Dokal
Publikováno v:
Cancer Research. 81:5765-5776
Cholangiocarcinoma is a form of hepatobiliary cancer with an abysmal prognosis. Despite advances in our understanding of cholangiocarcinoma pathophysiology and its genomic landscape, targeted therapies have not yet made a significant impact on its cl
Autor:
Daniel Osorio, Marieke L. Kuijjer, John Quackenbush, Camila M. Lopes-Ramos, Tess H. Brunner, Tatiana Belova, Marouen Ben Guebila
Publikováno v:
Cancer Res
Glioblastoma is an aggressive cancer of the brain and spine. While analysis of glioblastoma ‘omics data has somewhat improved our understanding of the disease, it has not led to direct improvement in patient survival. Cancer survival is often chara
Publikováno v:
Cancer Research, 81(18), 4874-4885. American Association for Cancer Research Inc.
Cancer Res
Cancer Res
Altered mechanical properties of the tumor matrix have emerged as both the cause and consequence of breast carcinogenesis. Increased tumor stiffness has traditionally provided a viable metric to screen for malignancies via palpation or imaging. Previ
Autor:
Yanmei Yi, Rong Jin, Hanmei Bao, Bing Li, Xiaohong Li, Nejat K. Egilmez, Di Yin, Edward R. Sauter, Yuan Hua, Jiaqing Hao, Xianlin Han
Publikováno v:
Cancer Res
The most recent American Dietary Guidelines (2020–2025) recommend shifting dietary fats from solid saturated fats to unsaturated oils. Dietary oils contain different compositions of unsaturated fatty acids (UFA). Oleic acid (OA) and linoleic acid (
Autor:
Kerry S. Courneya, Nawaid Usmani, Emily Heer, Andria R. Morielli, Lin Yang, Christine M. Friedenreich, Amy A. Kirkham, Winson Y. Cheung
Publikováno v:
Cancer Research. 81:4889-4895
We systematically reviewed and synthesized evidence on the impact of physical activity/exercise on cancer treatment efficacy. We included six preclinical and seven clinical studies. Exercise significantly enhanced the efficacy of chemotherapy and tam
Autor:
Dong Jun Lim, Chulhong Kim, Jeesu Kim, Sanjiv S. Gambhir, Chaiho Jeong, Byullee Park, Jeonghoon Ha, Idan Steinberg, Eun-Yeong Park, Yong-Min Kim, Tie Liang, Ja Seong Bae, Ravi Managuli, Wonseok Choi, Sarah M. Hooper
Publikováno v:
Cancer Research. 81:4849-4860
Thyroid cancer is one of the most common cancers, with a global increase in incidence rate for both genders. Ultrasound-guided fine-needle aspiration is the current gold standard to diagnose thyroid cancers, but the results are inaccurate, leading to
Autor:
Tengteng Wang, Michelle D. Holmes, Bernard Rosner, A. Heather Eliassen, Rulla M. Tamimi, Jae H. Kang, Walter C. Willett, Maryam S. Farvid
Publikováno v:
Cancer Res
Type II diabetes is associated with poor breast cancer prognosis. To study the association between a diabetes risk reduction diet (DRRD) and survival following breast cancer, we followed 8,482 women with breast cancer from two large cohort studies. I