Zobrazeno 31 - 40
of 1 309
pro vyhledávání: '"35"'
Autor:
Tianyi Tang, Ritesh Parajuli, Min-Ying Su, Chaitali Singh Nangia, Rita S. Mehta, Yu Cheng, Neha Patel
Publikováno v:
Cancer Research. 81:PS5-32
Background: The combination of anastrozole and fulvestrant (A+F) is associated with improvement in overall survival (OS) as compared to anastrozole (A) in patients (pts) with hormone receptor-positive (HR+) breast cancer (BC), specifically in pts wit
Autor:
Thibaut Sanglier, D. Tesarowski, Patricia Luhn, Eleonora Restuccia, Anita Fung, Carlos Flores, Preet K. Dhillon, Devin Incerti, Vincent Antao
Publikováno v:
Cancer Research. 81:PS10-20
OBJECTIVES Over the last decade, new treatment options have transformed the standard of care for patients (pts) with HER2-positive EBC and the treatment landscape continues to evolve. The primary objectives of our study were (1) to describe and compa
Autor:
Vinicius Xavier Santana, Mauro Pinto Passos, Natasha Garcia Caldas, Karoline Evangelista Souza, Natalia Polidorio, Thais Karla Vivan
Publikováno v:
Cancer Research. 81:PS7-81
Background: Even though breast cancer is uncommon in women ≤ age 35, women in this group are more likely to present aggressive cancer subtypes, advanced clinical stage at diagnosis and pathogenic variants (PV) in cancer susceptibility genes. Higher
Autor:
Tanja Fehm, Luc Dirix, Stefan Sleijfer, Paola Gazzaniga, José A. García-Sáenz, Carlos Caldas, Rita Zamarchi, Karthik V. Giridhar, Lorenzo Gerratana, Massimo Cristofanilli, Luis Manso, Dimitrios Mavroudis, Kostandinos Sideras, Meredith M. Regan, Zefei Jiang, Michail Ignatiadis, Rafael Gisbert-Criado, William E. Barlow, François-Clément Bidard, Thomas W. P. Friedl, Klaus Pantel, Evi Lianidou, Daniele Generali, Jean-Yves Pierga, Sabine Riethdorf, Tracy C. Yab, Mark Jesus M. Magbanua, Jose Vidal-Martinez, Jeffrey B. Smerage, Brigitte Rack, Hope S. Rugo, Catherine Alix-Panabières, Lisa A. Carey, Minetta C. Liu, Volkmar Müller, William Jacot, Wolfgang Janni, Elisabetta Munzone, Justin Stebbing, Leon W.M.M. Terstappen, Daniel F. Hayes
Publikováno v:
Cancer Research. 81:GS4-08
Background: Several studies suggest clinical utility of serial circulating tumor cell (CTC) enumeration as a means of assessing response status in metastatic breast cancer (MBC). The aim of this study is to conduct a comprehensive pooled analysis com
Autor:
Brent N. Rexer, Melinda E. Sanders, Paula I. Ericsson-Gonzalez, Ingrid A. Mayer, Adam Brufsky, Barbara Haley, Carlos L. Arteaga, Vandana G. Abramson, Erica Stringer-Reasor, Fei Ye, Komal Jhaveri
Publikováno v:
Cancer Research. 81:PD1-03
Background: Somatic alterations in the FGFR pathway (mainly FGFR1, amplified in about 15% of ER+ BC) have been implicated in resistance to endocrine therapy (ET), and more recently, to CDK4/6i as well. Based on our preclinical data showing that the F
Publikováno v:
Cancer Research. 80:P1-20
Purpose: Recently, some studies confirmed that the surgical margin in patients with breast fibromatosis was not associated with recurrence. Wide tumor-free resection surgery, which used to be the first-line treatment, might not be necessary for all f
Autor:
Matthew Blackburn, Claudine Isaacs, Ayesha N. Shajahan-Haq, Christopher Gallagher, Olwen Hahn, Filipa Lynce, Paula R. Pohlmann, Ming Tan, Ami Chitalia, Asma Dilawari, Maysa M. Abu-Khalaf, Mahsa Mohebtash, Robert D. Warren, Tianmin Wu, Shruti Tiwari, Rebecca Zhuo
Publikováno v:
Cancer Research. 80:P1-19
Background: There are significant racial disparities in breast cancer outcomes between African American women (AAW) and Caucasian women (CW) in the US. It has been reported that AAW have more chemotherapy dose reductions than CW which results in wors
Autor:
David Miles, Matthew Kent, Kenneth Russell, Mary K Downer, Patricia Luhn, Joyce O'Shaughnessy
Publikováno v:
Cancer Research. 80:P2-15
Background: Corticosteroids (CS) have immunosuppressive properties that may diminish the efficacy of cancer immunotherapy (CIT). In retrospective analyses of clinical trial data, the use of CS for immune-mediated adverse events after starting CIT doe
Autor:
Celine M. Vachon, Karthik V. Giridhar, Rachel A. Freedman, Fergus J. Couch, Robert W. Mutter, Roberto A. Leon-Ferre, Rafael E. Jimenez, Sadia Choudhery, Tina J. Hieken, John R. Hawse, Kathryn J. Ruddy, Nilay Shah, Lindsey R. Sangaralingham, Stephanie Payne, Judy C. Boughey, Siddhartha Yadav
Publikováno v:
Cancer Research. 80:P4-17
Background: The clinical utility of routine annual mammogram after curative-intent treatment for male breast cancer is uncertain. There is potentially greater value after lumpectomy (as surveillance for ipsilateral recurrence) than mastectomy (as scr
Autor:
Vardiella Meiner, Aviya Kedmi, Luna Kaduri, Albert Grinshpun, Shiri Shkedi, Tamar Hamburger, Ofra Maimon, Tamar Peretz
Publikováno v:
Cancer Research. 80:P5-08
Introduction: There are several reports of an earlier age of diagnosis in successive generation among BRCA1/2 mutation carriers' families, which may indicate an anticipation phenomenon among hereditary breast cancer (BC) patients. Here, we assess for