Zobrazeno 1 - 10
of 124
pro vyhledávání: '"35"'
Autor:
Danielle M. Friedrichsen, Janet R. Daling, Mariela C. Humphrey, Brian L. Strom, Nicola M. Suter, Jill A. McDonald, David R. Doody, Robert Spirtas, Polly A. Marchbanks, Ralph J. Coates, Ronald T. Burkman, Linda K. Weiss, Sandra A. Norman, Elaine A. Ostrander, Li Hsu, Jennifer Madeoy, Kathleen E. Malone, Dennis Deapen, Suzanne G. Folger, Michael S. Simon, Giske Ursin, Leslie Bernstein
Publikováno v:
Cancer research. 66(16)
Although well studied in families at high-risk, the roles of mutations in the BRCA1 and BRCA2 genes are poorly understood in breast cancers in the general population, particularly in Black women and in age groups outside of the very young. We examine
Autor:
Michael S. Simon, Yani Lu, Jane Sullivan-Halley, Michael F. Press, Brian L. Strom, Leslie Bernstein, Kathleen E. Malone, Huiyan Ma, Dennis Deapen
Publikováno v:
Cancer Research. 72:3590-3590
Purpose: To evaluate the extent to which the black-white disparity in mortality following breast cancer diagnosis is explained by the expression status of four biomarkers - estrogen receptor (ER), progesterone receptor (PR), human epidermal growth fa
Autor:
David Miles, Matthew Kent, Kenneth Russell, Mary K Downer, Patricia Luhn, Joyce O'Shaughnessy
Publikováno v:
Cancer Research. 80:P2-15
Background: Corticosteroids (CS) have immunosuppressive properties that may diminish the efficacy of cancer immunotherapy (CIT). In retrospective analyses of clinical trial data, the use of CS for immune-mediated adverse events after starting CIT doe
Autor:
Henry L. Gomez, Daniel J Enriquez, Eduardo Eyzaguirre, Silvia P. Neciosup, Renato Luque, Joseph A. Pinto, Hugo Fuentes, Antonella Saavedra, Maria Lujan, Zaida Morante, G De la Cruz-Ku
Publikováno v:
Cancer Research. 78:P1-15
Background: Triple-negative breast cancer (TNBC) in young and older patients has specific features and outcomes. While in younger patients, it is characterized by being aggressive with worse survival, in advanced ages it may have a better outcome whi
Publikováno v:
Cancer Research. 77:P5-10
Background: Breast cancer (BC) is the most common malignancy and leading cause of cancer death in women. BC incidence is lower in Hispanic (H) (91.9/100,000) compared to non-Hispanic Whites (NHW -128.1/100.000) and Non-Hispanic Black (NHB - 124.3/100
Autor:
Hwi-Won Lee, Jae Jeong Yang, Jong Koo Lee, Aesun Shin, Woo-Kyoung Shin, Daehee Kang, Minkyo Song
Publikováno v:
Cancer Research. 80:LB-157
Background: The global trend of obesity, or the “obesity epidemic,” is not confined to adults. The increasing rates of obesity at young age signifies potential burden to our society as a whole, and requires prompt attention. Although emerging evi
Autor:
T Mancuso, T Graham, Karen Ott, Paul Hewitt, Andrea Eisen, J Lorentz, M Emmerson, Jacques Raphael
Publikováno v:
Cancer Research. 76:P6-10
Background Women with identified BRCA1/2 mutation have a substantially increased risk of developing several types of cancer, mainly breast and ovarian, during their lifetime. Management options included close surveillance, chemoprevention and prophyl
Autor:
Sheldon Feldman, Matthew Maurer, S Refice, Bret Taback, Kevin Kalinsky, Dawn L. Hershman, Katherine D. Crew, Hanina Hibshoosh, Eileen P. Connolly, Tian Zheng
Publikováno v:
Cancer Research. 75:P6-12
Background: Laboratory and population studies demonstrate that metformin offers a beneficial breast cancer (BC) effect. In vitro, metformin has been shown to induce cycle cycle arrest. In a pre-surgical metformin trial of overweight/obese, multi-ethn
Autor:
Musa Mayer, Mary Beattie, Sara A. Hurvitz, Adam Brufsky, Bongin Yoo, Denise A. Yardley, Hope S. Rugo, Mohammad Jahanzeb, Sandra M. Swain, Peter A. Kaufman, Joyce O'Shaughnessy, Ginny Mason, Debu Tripathy, Melody A. Cobleigh
Publikováno v:
Cancer Research. 75:P3-07
Introduction The Systemic Therapies for HER2-Positive Metastatic Breast Cancer Registry (SystHERs) is a US-based prospective observational cohort study currently enrolling patients with HER2-positive metastatic breast cancer (MBC). It began in 2012 a
Autor:
Bonnie DePalma, Reshma Jagsi, Eleanor M. Walker, Nirav S. Kapadia, Thy Thy Do, Yolanda R. Helfrich, Kent A. Griffith, Alexandria Miller, Dean A. Shumway, Adam L. Liss, Erin F. Gillespie, Mary Feng, Lori J. Pierce
Publikováno v:
Cancer Research. 75:P1-15
Purpose Scales for rating acute radiation dermatitis (ARD) are inconsistent and have not been validated despite decades of clinical use, making ARD difficult to report reliably. We sought to design a photonumeric scale to consistently describe ARD in