Zobrazeno 1 - 10
of 483
pro vyhledávání: '"11"'
Autor:
Camilla Stavnsbjerg, Thomas Lars Andresen, Anders Elias Hansen, Lars Ringgaard, Andreas Kjaer, Lotte K. Kristensen, Esben Christensen
Publikováno v:
Cancer Research. 79:1528-1528
The tumor microenvironment (TME) composition is a critical parameter for therapeutic outcome in cancer patients. Understanding the TME composition and influence on anti-cancer therapies is a valuable tool for developing new treatments. High TME infil
Publikováno v:
Cancer Research. 78:2620-2620
Background: Biomarkers predictive of response to chemotherapy are critically needed for the precise selection of treatment protocols in lung adenocarcinoma (LUAD). Aquaporins (AQPs), transmembrane water channels, are emerging targets in cancer. Recen
Autor:
Taiga Nishihori, Allison Distler, John Powers, Javier Pinilla-Ibarz, Melissa Alsina, Mark B. Meads, Jason Brayer, Eduardo M. Sotomayor, Rachid Baz, Kenneth H. Shain, Alejandro Villagra, Eva Sahakian, Susan Deng
Publikováno v:
Cancer Research. 74:5537-5537
Initially studied mainly for its role as a regulator of neural cell differentiation and development, expression of HDAC11 was once thought to be restricted exclusively to brain, kidney and testes. Hence, our recent discovery that HDAC11 acts as an im
Autor:
Paul Cottu, Xavier Sastre-Garau, François-Clément Bidard, Delphine Loirat, Leonor Chaltiel, Youlia M. Kirova, Séverine Alran, Frédérique Berger, Yann De Rycke, Jean-Yves Pierga, Anne Vincent Salomon, Véronique Diéras
Publikováno v:
Cancer Research. 75:P4-03
Background: BM DTC detection is known to be a prognostic factor for distant metastasis and overall survival in early breast cancer. However, distant relapses may occur in patients with no DTC detected at time of primary cancer. In this study, we stud
Autor:
Guohua Zhang, James Z. Zhu, Min Li, Yan Zuo, Jeffrey A. Frost, Zicheng Zhang, Yi-Ping Li, Thomas K. Sin
Publikováno v:
Cancer Res
Cancer-associated cachexia, characterized by muscle wasting, is a lethal metabolic syndrome without defined etiology or established treatment. We previously found that p300 mediates cancer-induced muscle wasting by activating C/EBPβ, which then upre
Autor:
Jose Luis Solorzano, Cristina Cirauqui, Irene Ferrer, Maria T. Muñoz, Javier Ramos-Paradas, Laura Ojeda, Patricia Yagüe, Sonia Molina-Pinelo, Nuria Carrizo, Luis Paz-Ares, Ana Belén Enguita, Alba Santos, Eva M. Garrido-Martin
Publikováno v:
Cancer Research. 80:5247-5247
Interleukin-11 (IL11) has been associated with tumorigenesis in a wide variety of tumors, including lung cancer, and it has been proposed as a diagnostic biomarker for lung adenocarcinoma. However, it is still not clear how IL11 affects the tumorigen
Autor:
Wadih Arap, Amado J. Zurita, Patricia Troncoso, Christopher J. Logothetis, Renata Pasqualini, Marina Cardó-Vila
Publikováno v:
Cancer Research. 64:435-439
Direct screening of combinatorial peptide libraries in patients may allow the identification of ligands that target biochemical differences in the endothelium of blood vessels. In a screening performed in a patient, we selected and isolated a mimic m
Autor:
Patrick O'Hayer, Euisik Yoon, Elisa Boscolo, Alexander T. Pearson, Yashar S. Niknafs, Joyce Bischoff, Yu Chih Chen, Ronald J. Buckanovich, Yun Wang, Ning Deng, Patrick Ingram, Zhong Yin Zhang, Shoumei Bai
Publikováno v:
Cancer research. 76(21)
Little is known about the factors that regulate the asymmetric division of cancer stem–like cells (CSC). Here, we demonstrate that EGFL6, a stem cell regulatory factor expressed in ovarian tumor cells and vasculature, regulates ALDH+ ovarian CSC. E
Autor:
Catherine Tomasetto, Elena Roza Motrescu, Marie-Pierre Chenard, Marie-Christine Rio, Kumari L. Andarawewa, Anne Gansmuller, Isabelle Stoll
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2005, 65 (23), pp.10862-71. ⟨10.1158/0008-5472.CAN-05-1231⟩
Cancer Research, American Association for Cancer Research, 2005, 65 (23), pp.10862-71. ⟨10.1158/0008-5472.CAN-05-1231⟩
The initial invasive processes during cancer development remain largely unknown. Stromelysin-3/matrix metalloproteinase 11 (ST3/MMP11) is associated with tumor invasion and poor prognosis. We present novel evidence that adipocytes present at human br
Autor:
Marjan Boerma, Junru Wang, Alexander F. Burnett, Martin Hauer-Jensen, Juan J. Roman, Alessandro D. Santin
Publikováno v:
Cancer Research. 67:9501-9506
Intestinal radiation injury is dose limiting during abdominal and pelvic radiotherapy and critical for the outcome after accidental whole-body radiation exposure. The multifunctional cytokine, interleukin-11 (IL-11), ameliorates the intestinal radiat