Zobrazeno 1 - 10
of 18
pro vyhledávání: '"33"'
Autor:
Xiwei Sun, Angli Xue, Yang Wu, Jian Yang, Ting Qi, Dan Chen, Dandan Shi, Jian Zeng, Zhili Zheng
Publikováno v:
Br J Cancer
Tumor mutational burden (TMB) is an emerging biomarker of response to immunotherapy in solid tumors. However, the extent to which variation in TMB between patients is attributable to germline genetic variation remains elusive. Here, using 7,004 unrel
Publikováno v:
Cancer research. 49(18)
Immunogenetic evidence suggests a genetic association between the major histocompatibility complex and the two genitourinary neoplasms, testicular teratocarcinoma and renal cell carcinoma. In order to develop a possible explanation for these findings
Autor:
Robert R, Langley, Karen M, Ramirez, Rachel Z, Tsan, Melissa, Van Arsdall, Monique B, Nilsson, Isaiah J, Fidler
Publikováno v:
Cancer research. 63(11)
Microvascular endothelial cells play a critical role in tumor progression and metastasis by forming capillary networks that encourage tumor growth and by promoting the attachment of circulating tumor cells to the vascular wall of distant tissues. Eff
Autor:
F A, Blommaert, C, Michael, P M, Terheggen, F M, Muggia, V, Kortes, J H, Schornagel, A A, Hart, L, den Engelse
Publikováno v:
Cancer research. 53(23)
Twenty-six patients with a variety of tumor types were treated according to a phase 1 experimental treatment protocol consisting of repetitive cycles of cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II) (carboplatin, 200-480 mg/m2) at day 1 and
Publikováno v:
Cancer research. 53(20)
Pharmacokinetic studies of etoposide administered at 100-200 mg/m2 to 33 children are described. Twenty-seven studies were performed in children aged10 years. Repeat studies were performed in 11 patients. Median pharmacokinetic parameters were as fol
Publikováno v:
Cancer research. 36(9 pt.1)
Lymphocyte-stimulated protein synthesis (SPS) in response to human tumor-associated antigens was assessed by measuring [3H]leucine incorporation. Correlation of SPS with other in vivo and in vitro response was demonstrated by immunizing normal subjec
Autor:
A, Oikawa, K, Horaguchi, R, Sugawara, J, Kikuchi, H, Tohda, K, Takahashi, A, Wakui, A, Yamauchi, T, Nakada
Publikováno v:
Cancer research. 46(2)
Sensitivities to sister chromatid exchange (SCE) induction by chemicals of peripheral lymphocytes from 26 cancer patients were estimated under conditions identical to those for healthy humans which had been reported (Cancer Res., 43: 439-442, 1983).
Publikováno v:
Cancer research. 43(10)
The effects of calcium and magnesium acetates on the formation of injection site and testicular tumors in male Wistar rats over 2 years following s.c. injections of cadmium chloride (CdCl2) were determined. The rats (25/group) received a single s.c.
Publikováno v:
Cancer research. 48(19)
The formation and stability of interaction products between the anti-cancer drug cis-diamminedichloroplatinum(II) (cis-DDP) and DNA were studied in buccal epithelial and urinary cells from ten cancer patients who received cis-DDP-based therapy. Bucca
Publikováno v:
Cancer research. 48(6)
19F NMR spectroscopy at 470 MHz (11.7 Tesla) has been used to directly measure the levels of 5-fluorouracil (FU) and its fluorine-containing catabolites in plasma and urine of colon cancer patients after i.v. infusion (10 min) of 60-230 mumol (8-30 m