Zobrazeno 1 - 10
of 71
pro vyhledávání: '"11"'
Autor:
Guohua Zhang, James Z. Zhu, Min Li, Yan Zuo, Jeffrey A. Frost, Zicheng Zhang, Yi-Ping Li, Thomas K. Sin
Publikováno v:
Cancer Res
Cancer-associated cachexia, characterized by muscle wasting, is a lethal metabolic syndrome without defined etiology or established treatment. We previously found that p300 mediates cancer-induced muscle wasting by activating C/EBPβ, which then upre
Autor:
Patrick O'Hayer, Euisik Yoon, Elisa Boscolo, Alexander T. Pearson, Yashar S. Niknafs, Joyce Bischoff, Yu Chih Chen, Ronald J. Buckanovich, Yun Wang, Ning Deng, Patrick Ingram, Zhong Yin Zhang, Shoumei Bai
Publikováno v:
Cancer research. 76(21)
Little is known about the factors that regulate the asymmetric division of cancer stem–like cells (CSC). Here, we demonstrate that EGFL6, a stem cell regulatory factor expressed in ovarian tumor cells and vasculature, regulates ALDH+ ovarian CSC. E
Autor:
Catherine Tomasetto, Elena Roza Motrescu, Marie-Pierre Chenard, Marie-Christine Rio, Kumari L. Andarawewa, Anne Gansmuller, Isabelle Stoll
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2005, 65 (23), pp.10862-71. ⟨10.1158/0008-5472.CAN-05-1231⟩
Cancer Research, American Association for Cancer Research, 2005, 65 (23), pp.10862-71. ⟨10.1158/0008-5472.CAN-05-1231⟩
The initial invasive processes during cancer development remain largely unknown. Stromelysin-3/matrix metalloproteinase 11 (ST3/MMP11) is associated with tumor invasion and poor prognosis. We present novel evidence that adipocytes present at human br
Autor:
Marjan Boerma, Junru Wang, Alexander F. Burnett, Martin Hauer-Jensen, Juan J. Roman, Alessandro D. Santin
Publikováno v:
Cancer Research. 67:9501-9506
Intestinal radiation injury is dose limiting during abdominal and pelvic radiotherapy and critical for the outcome after accidental whole-body radiation exposure. The multifunctional cytokine, interleukin-11 (IL-11), ameliorates the intestinal radiat
Autor:
Xiao-Ming Shen, Ming-Rong Wang, Man-Li Luo, Xun Zhang, Yu Zhang, Fang Wei, Min Wu, Yan Cai, Xin Xu, Qimin Zhan, Yuntian Sun
Publikováno v:
Cancer Research. 66:11690-11699
Gain of chromosome 11q13 is a common event in esophageal squamous cell carcinoma (ESCC). The cortactin gene (CTTN, also EMS1), located at 11q13, plays a pivotal role in coupling membrane dynamics to cortical actin assembly. This gene has been implica
Autor:
Vladimir Janout, Christine Carreira, Michael Pawlita, Devasena Anantharaman, H. Bas Bueno-de-Mesquita, Lenka Foretová, Massimo Tommasino, Paul Brennan, Françoise Clavel-Chapelon, Dana Mates, Eleonora Fabianova, J. Ramón Quirós, Behnoush Abedi-Ardekani, Mikael Johansson, Jolanta Lissowska, Vittorio Krogh, David Zaridze, Gordana Halec, Elisabete Weiderpass, Peter Rudnai, Neonila Szeszenia-Dabrowska, H. Boeing, Mattias Johansson, Anastasia Kotanidou, Anne Tjønneland, Tarik Gheit, Tim Waterboer, Ghislaine Scelo, Ruth C. Travis, Sandrine McKay-Chopin, Anush Mukeria, Vladimir Bencko
Publikováno v:
Cancer research. 74(13)
Human papillomavirus (HPV) infections have been implicated in lung carcinogenesis, but causal associations remain uncertain. We evaluated a potential causal role for HPV infections in lung cancer through an analysis involving serology, tumor DNA, RNA
Autor:
Nathaniel D. Anderson, Jonathan D. Wasserman, Ana Stosic, Fabio Fuligni, Evan J. Propst, Scott Davidson, Nikolaus E. Wolter, Meryl Acker, Richard de Borja, Ozgur Mete, Rose Chami, Adam Shlien, Vito Forte, David Malkin, Paolo Campisi
Publikováno v:
Cancer Research. 81:5625-5637
Pediatric papillary thyroid carcinoma (PPTC) is clinically distinct from adult-onset disease. Although there are higher rates of metastasis and recurrence in PPTC, prognosis remains highly favorable. Molecular characterization of PPTC has been lackin
Autor:
Yin-Yuan Mo, Mohit Sachdeva
Publikováno v:
Cancer research. 70(1)
MicroRNAs are important gene regulators that could play a profound role in tumorigenesis. Our previous studies indicate that miR-145 is a tumor suppressor capable of inhibiting tumor cell growth both in vitro and in vivo. In this study, we show that
Autor:
Annick Vieillefond, Bart O. Williams, Charis Eng, Chao-Nan Qian, Aaron Massie, Sok Kean Khoo, Vincent Molinié, Karl Dykema, Eva Comperat, Jared Knol, Kyle A. Furge, James H. Resau, Mathilde Sibony, Jindong Chen, Bin Tean Teh, Dan Huang, Kristin Vanden Beldt, Yves Denoux, Eric J. Kort, Philippe Camparo, John Anema, Richard J. Kahnoski, Hans Morreau
Publikováno v:
Cancer research. 69(21)
Urothelial carcinoma of the renal pelvis is a deadly disease with an unclear tumorigenic mechanism. We conducted gene expression profiling on a set of human tumors of this type and identified a phosphatidylinositol 3-kinase (PI3K)/AKT activation expr
Autor:
Zheng-Zheng Yu, Song-Qing Fan, Wei Zhu, Hong Yi, Xueping Feng, Ta Xiao, Juan Feng, Wei Huang, Shan-Shan Lu, Jiao-Yang Li, Guo-Hui Nie, Zhi-Qiang Xiao, Song Gao, Yaoyun Tang
Publikováno v:
Cancer research. 80(20)
Overexpression of ANXA1 and EphA2 has been linked to various cancers and both proteins have attracted considerable attention for the development of new anticancer drugs. Here we report that ANXA1 competes with Cbl for binding EphA2 and increases its