Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Xiaoyan Wang"'
Autor:
Geoffrey Bartholomeusz, Xiao Feng Le, Robert C. Bast, Geoffrey Grandjean, Bradley M. Broom, Juliet Goldsmith, Xiaoyan Wang, Ahmed Ashour Ahmed, Zhen Lu
Publikováno v:
Cancer Research. 71:5806-5817
The extracellular matrix protein TGFBI enhances the cytotoxic response of cancer cells to paclitaxel by affecting integrin signals that stabilize microtubules. Extending the implications of this knowledge, we tested the more general hypothesis that c
Autor:
William H. Fleming, Derek Zachman, Anupriya Agarwal, Xiaoyan Wang, Mahnaz Janghorban, Rosalie C. Sears
Publikováno v:
Cancer Research. 75:3180-3180
Protein phosphatase 2 A (PP2A) is one of the major cellular Serine-Threonine phosphatases and regulates numerous signaling pathways, including stem cell self-renewal, proliferation, differentiation, and cell survival. The PP2A holoenzyme has 3 subuni
Autor:
Rosalie C. Sears, Colin J. Daniel, Mahnaz Janghorban, Yulong Su, Xiaoyan Wang, Carl Pelz, Soren Impey, Amy Farrell
Publikováno v:
Cancer Research. 73:771-771
The c-Myc oncoprotein is generally considered to be a master regulator of gene transcription by virtue of its ability to activate or repress the expression of a large percentage of all genes. However, mechanisms that direct c-Myc's recruitment to DNA
Publikováno v:
Cancer Research. 73:953-953
Virtually all patients with newly diagnosed ovarian cancer are treated with a combination of paclitaxel and carboplatin. While 70% of ovarian cancers respond to carboplatin, more than half do not respond to the paclitaxel. Inhibition of kinases that