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pro vyhledávání: '"929"'
Autor:
Jinsuk Kang
Publikováno v:
Cancer Research. 81:929-929
STAT3 functions are largely bifurcated: (1) STAT3 activated by Y705 phosphorylation (pY705) regulates target-gene expression in nucleus. (2) STAT3 activated by S727 phosphorylation (pS727) supports a electron transport complex (ETC) in mitochondria.
Autor:
Oscar Arrieta, R. Bernabé, Judith Dalmau, Miguel Angel Molina-Vila, Jorge Carrillo, Remedios Blanco, Teresa Moran, Clara Mayo de las Casas, Jillian Wilhelmina Paulina Bracht, Bonaventura Clotet, Christian Brander, Jordi Argilaguet, Julia G. Prado, Mariano Provencio, Javier Garcia-Corbacho, Ana Giménez-Capitán, Mónica Garzón, Erika Aldeguer, Andrés F. Cardona, Rafael Rosell, Bartomeu Massuti, Javier de Castro, Maria Gonzalez-Cao, Javier Martinez-Picado, Andreas Meyerhans, Sonia Rodríguez, Oscar Juan, Ana Drozdowskyj, Chung-Ying Huang, J. Blanco
Publikováno v:
Cancer Research. 80:929-929
Introduction: Treatment with anti PD-1/PD-L1 antibodies has demonstrated clinical activity in different types of solid tumors, but only 20 to 30% of patients (pts) respond to these immune checkpoint inhibitors (ICIs). Therefore, predictive biomarkers
Autor:
Noopur Shah, Fang Liu, Hubert Maehr, Amanda K. Smolarek, Milan R. Uskokovic, Jae Young So, Nanjoo Suh
Publikováno v:
Cancer Research. 72:929-929
CD44, a transmembrane glycoprotein, is highly expressed in breast tumors, and the overexpression of CD44 has been associated with poor clinical outcome. CD44 has been known to play a key role in invasive growth of cancer by interacting with extracell