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pro vyhledávání: '"929"'
Autor:
Oscar Arrieta, R. Bernabé, Judith Dalmau, Miguel Angel Molina-Vila, Jorge Carrillo, Remedios Blanco, Teresa Moran, Clara Mayo de las Casas, Jillian Wilhelmina Paulina Bracht, Bonaventura Clotet, Christian Brander, Jordi Argilaguet, Julia G. Prado, Mariano Provencio, Javier Garcia-Corbacho, Ana Giménez-Capitán, Mónica Garzón, Erika Aldeguer, Andrés F. Cardona, Rafael Rosell, Bartomeu Massuti, Javier de Castro, Maria Gonzalez-Cao, Javier Martinez-Picado, Andreas Meyerhans, Sonia Rodríguez, Oscar Juan, Ana Drozdowskyj, Chung-Ying Huang, J. Blanco
Publikováno v:
Cancer Research. 80:929-929
Introduction: Treatment with anti PD-1/PD-L1 antibodies has demonstrated clinical activity in different types of solid tumors, but only 20 to 30% of patients (pts) respond to these immune checkpoint inhibitors (ICIs). Therefore, predictive biomarkers
Autor:
Max S. Wicha, Michael D. Brooks
Publikováno v:
Cancer Research. 77:929-929
The CSC hypothesis posits that there is a subset of tumors cells driving tumor growth and metastasis and that by targeting this population, tumors can be more efficiently eradicated. Recently it was shown that there are two types of CSCs in breast ca
Autor:
Noopur Shah, Fang Liu, Hubert Maehr, Amanda K. Smolarek, Milan R. Uskokovic, Jae Young So, Nanjoo Suh
Publikováno v:
Cancer Research. 72:929-929
CD44, a transmembrane glycoprotein, is highly expressed in breast tumors, and the overexpression of CD44 has been associated with poor clinical outcome. CD44 has been known to play a key role in invasive growth of cancer by interacting with extracell
Autor:
Bradley M. Turner, Danielle E. Desa, Edward B. Brown, Brandon Buscaglia, Robert L. Strawderman, Robert L. Hill, David G. Hicks
Publikováno v:
Cancer Research. 79:P6-09
Background: Over-expression of Human Epidermal Growth Factor receptor-2 (HER2) in breast cancer is associated with an aggressive clinical course and poor prognosis. Targeting HER2 over-expression has been shown to be a remarkably effective therapeuti
Autor:
Anna E. Coghill, Andrea N. Burnett-Hartman, Michael N. Passarelli, Polly A. Newcomb, Karen W. Makar
Publikováno v:
Cancer Research. 72:1671-1671
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL The prostaglandin synthesis pathway is critical for regulation of inflammatory processes in the colon and plays a well-defined role in colorectal carcinogenesis. Gene
Publikováno v:
Cancer Research. 69:4105
Abstract #4105 Introduction: The decision to treat women with hormone receptor-positive breast cancer with chemotherapy in addition to hormonal therapy is complex. Models have been developed to assist physicians in estimating survival benefit associa