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Autor:
Chelsea Jin, Maher Albitar, Vladislav Chizhevsky, Virginia Burns, Sucha Sudarsanam, Cory Batenchuk
Publikováno v:
Cancer Research. 77:4015-4015
Background: Higher levels of PD-L1 expression at the surface of tumor cells have been associated with increased response to anti-PD-1 therapies (Santabarbara G et al. Ann Transl Med. 2016;4:215; Borghaei H et al. N Engl J Med. 2015;373:1627-1639; Bra
Autor:
Christian U. Blank, Michal Lotem, Clemens Krepler, Teresa M. Petrella, Matteo S. Carlino, Caroline Robert, Georgina V. Long, Paul Lorigan, Antoni Ribas, James Larkin, Omid Hamid, Laurent Mortier, Jean-Jacques Grob, James R. Anderson, Catriona M. McNeil, Scott J. Diede, Bart Neyns, Ana Arance, Jacob Schachter, Adil Daud
Publikováno v:
Cancer Research. 79:CT188-CT188
Introduction: Pembro significantly improved OS vs ipi in advanced melanoma in the KEYNOTE-006 study (NCT01866319). We present outcomes from the 5-year follow-up of this study−the longest to date in a randomized phase 3 trial of pembro in advanced c