Zobrazeno 71 - 80
of 91
pro vyhledávání: '"35"'
Autor:
Lai-Meng Looi, Cheng Har Yip, Nur Aishah Taib, Sze-Yee Phuah, Soo-Hwang Teo, Anthony Rhodes, Sarah Dean
Publikováno v:
Cancer Research. 72:2609-2609
Background: Given that BRCA1 carriers are more likely to develop triple negative breast cancers (TNBC) and that current risk assessment models underestimate BRCA carriers in Asian populations, we have sought to determine the prevalence of BRCA mutati
Publikováno v:
Cancer Research. 72:2740-2740
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive human malignancies characterized by late clinical presentation, rapid local and metastatic progression and high resistance to conventional therapies. Gemcitabine, an approved treat
Autor:
Shoko Kure, Taeko Suzuki, Kazuya Yamahatsu, Tetsushi Yamamoto, Junji Ueda, Masahito Hagio, Yoko Matsuda, Zenya Naito, Toshiyuki Ishiwata
Publikováno v:
Cancer Research. 72:412-412
Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high incidence of distant metastasis. Recent studies have shown that cancer stem cells (CSCs) are important in cancer cell growth, invasion, metastasis, and recurr
Autor:
J Gariepy, A Abdul-Wahid
Publikováno v:
Cancer Research. 71:P1-01
Background: The carcinoembryonic antigen (CEA) is over-expressed in ∼56% of breast cancer biopsies but is absent on normal breast tissues. Clinically, high preoperative serum concentrations of CEA in breast cancer patients correlate with metastasis
Autor:
Yi-Chen Li, Ann-Joy Cheng
Publikováno v:
Cancer Research. 71:26-26
Oral cancer is the 6th most frequent cancer in Taiwan. The habit of areca nut chewing is the main etiological factor of oral cancer. To shed light on molecular basis of areca nut associated oral carcinogenesis, we established two oral cell sublines c
Autor:
Ronald Nines, Yufen Wang, Tong Chen, Fei Yan, Alexandria M. Edmonds, Xin Huang, Huaji Guan, Carter Battista, Gary D. Stoner
Publikováno v:
Cancer Research. 71:819-819
Esophageal cancer is the 6th most common cancer worldwide. Our laboratory has used a rodent preclinical model of esophageal squamous cell carcinoma to identify putative chemopreventive agents for this disease and to determine their mechanisms of acti
Autor:
Carter Battista, Alexandria M. Edmonds, Tong Chen, Fei Yan, Xin Huang, Gary D. Stoner, Huaji Guan, Ronald Nines, Yufen Wang
Publikováno v:
Cancer Research. 71:811-811
Hyperactivation of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) has been observed separately in esophageal squamous cell carcinoma (ESCC) in rats that is induced by N-nitrosomethylbenzylamine (NMBA), a powerful carcinogen found
Autor:
Kevin B. Chandler, Brent E. Korba, Ourania Kosti, Zuzana Brnakova, Ionut Bebu, Milos V. Novotny, Radoslav Goldman, Juraj Lenco, Kirti Shetty, Habtom W. Ressom, Rency S. Varghese, Slavka Bekesova
Publikováno v:
Cancer Research. 70:5569-5569
Purpose: Incidence of hepatocellular cancer (HCC) continues to increase primarily due to hepatitis C viral (HCV) infection. Prognosis and survival of patients is highly affected by the disease stage at the time of diagnosis. Our mass spectrometric st
Publikováno v:
Cancer Research. 70:960-960
The MMTV-Neu transgenic mouse develops Neu over-expressing ER− mammary cancers. Since human ER− Neu over-expressing mammary cancers often also have mutations in P53, a heterozygous KO of P53 was incorporated into the model. We have used this mode
Autor:
James B. Johnston, Donna Hewitt, Ju-Yoon Yoon, Brenda Kuschak, Spencer B. Gibson, Sunjay Lakhi
Publikováno v:
Cancer Research. 70:1762-1762
It has been suggested that cytokines play an important role in the survival and proliferation of chronic lymphocytic leukemia (CLL) cells and these growth factors may be derived from a variety of cell types, including CLL cells. The plasma levels of