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Autor:
Rami I. Aqeilan, Maria Sundvall, Marius Sudol, Johan Lundin, Anna Korhonen, Heikki Joensuu, Jorma Isola, Eugenio Gaudio, Valentina Donati, Carlo M. Croce, Klaus Elenius, Milena S. Nicoloso
Publikováno v:
Cancer Research. 67:9330-9336
WWOX, WW domain-containing oxidoreductase, is a tumor suppressor that is altered in many human cancers, including breast cancer. Wwox interacts with the ErbB4 receptor, reduces nuclear translocation of the cleaved intracellular domain of ErbB4, and i