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pro vyhledávání: '"556"'
Autor:
Richard E. Green, Christopher J. Troll, Abdullah Mahmood Ali, Camille Schwartz, Varsha Rao, Azra Raza, Charles J. Vaske, Kelly Harkins-Kincaid, Colin Naughton
Publikováno v:
Cancer Research. 81:556-556
DNA sequencing library preparation is a crucial step for next-generation sequencing of cell free DNA of plasma for cancer diagnostics. We present SRSLY, a robust single-stranded DNA library preparation method, that generates libraries with unique mol
Autor:
Gabriele Matschiner, Corinna Schlosser, Sven Berger, Marlon Hinner, Ulrich Moebius, Christine Rothe, Alexander Wiedenmann, Andrea Allersdorfer, Rachida-Siham Bel Aiba, Shane Olwill
Publikováno v:
Cancer Research. 76:556-556
Background. CD137 (4-1BB) is a key costimulatory immunoreceptor and a member of the TNF-receptor (TNFR) superfamily. While multiple lines of evidence show that CD137 is a highly promising therapeutic target in cancer, current mAb-based approaches are
Publikováno v:
Cancer Research. 74:556-556
Background: The pro-inflammatory cytokine, interleukin 32 (IL-32), is a novel tumor marker highly expressed in various human carcinomas including gastric cancer (GC). Materials and Methods: A total of 120 patients with gastric cancer undergoing gastr
Publikováno v:
Cancer Research. 71:556-556
Sulfatase 2 (Sulf2) is an extracellular enzyme which catalyzes the removal of 6-O-sulfate groups on glucosamine from subregions of the glycosaminoglycan heparin sulfate. Sulf2 action alters the binding of protein ligand growth factors such as VEGF, F
Autor:
Suzanne A. Eccles, Faith E. Davis, Gerhardt Attard, Gary Box, Simon P. Robinson, Johann S. de Bono, Timothy J. Graham
Publikováno v:
Cancer Research. 73:3924-3924
Prostate cancer (PCa) growth is incurable once it has metastasized to the bone microenvironment (BM). The altered BM provides a permissive niche to support tumour growth, and therapeutic strategies that target tumour-bone interactions and/or restore
Autor:
Jason W. H. Wong, Michael J. Bourke, John E. Pimanda, Mathew A. Sloane, Luke B. Hesson, Robyn L. Ward, Nicholas J. Hawkins
Publikováno v:
Cancer Research. 72:LB-375
Colorectal cancer (CRC) develops from intraepithelial neoplasms known as adenomas. Genomic profiling of these premalignant lesions presents an opportunity to discover molecular changes that can lead to colorectal cancer. Some of the earliest changes