Zobrazeno 1 - 10
of 23
pro vyhledávání: '"556"'
Autor:
John M. Maris, Laura E. Egolf, Diskin Sharon, Rebecca Kaufman, Alex Lee, Zalman Vaksman, Emily Blauel, Andrew F. Olshan
Publikováno v:
Cancer Research. 81:3030-3030
Background: Neuroblastoma is a childhood cancer that arises from the sympathetic nervous system. Approximately 1% of patients have a family history of disease with causal germline mutations in neuroblastoma predisposition genes, ALK or PHOX2B. Recent
Autor:
Richard E. Green, Christopher J. Troll, Abdullah Mahmood Ali, Camille Schwartz, Varsha Rao, Azra Raza, Charles J. Vaske, Kelly Harkins-Kincaid, Colin Naughton
Publikováno v:
Cancer Research. 81:556-556
DNA sequencing library preparation is a crucial step for next-generation sequencing of cell free DNA of plasma for cancer diagnostics. We present SRSLY, a robust single-stranded DNA library preparation method, that generates libraries with unique mol
Publikováno v:
Cancer Research. 74:556-556
Background: The pro-inflammatory cytokine, interleukin 32 (IL-32), is a novel tumor marker highly expressed in various human carcinomas including gastric cancer (GC). Materials and Methods: A total of 120 patients with gastric cancer undergoing gastr
Autor:
Tvrtko Hudolin, Giulio C. Spagnoli, Maurizio Provenzano, Lukas Bubendorf, Chantal Mengus, Tullio Sulser, Giovanni Sais, Stephen Wyler, Irina Banzola, Hans H. Hirsch
Publikováno v:
Cancer Research. 72:556-556
Background: Polyomavirus BK (BKV) large tumor antigen (L-Tag) contributes to oncogenesis by regulating crucial pathways of human cell cycle when non-permissive cells are infected. Therefore, L-Tag has been identified as an important target of immune
Publikováno v:
Cancer Research. 71:556-556
Sulfatase 2 (Sulf2) is an extracellular enzyme which catalyzes the removal of 6-O-sulfate groups on glucosamine from subregions of the glycosaminoglycan heparin sulfate. Sulf2 action alters the binding of protein ligand growth factors such as VEGF, F
Publikováno v:
Cancer Research. 70:556-556
Carcinoma Associated Fibroblasts (CAFs) along with other cells present in the tumor milieu play a major role in tumor progression. We have previously demonstrated differentiation of human bone marrow derived mesenchymal stem cells to CAF like phenoty
Publikováno v:
Cancer Research. 70:P2-06
Purpose: A strong prognostic impact of urokinase type plasminogen activator (uPA) and its inhibitor plasminogen activator inhibitor type 1 (PAI-1) as individual factors is well established, with a level of evidence I according to the ASCO recommendat
Autor:
Chelsea Jin, Maher Albitar, Vladislav Chizhevsky, Virginia Burns, Sucha Sudarsanam, Cory Batenchuk
Publikováno v:
Cancer Research. 77:4015-4015
Background: Higher levels of PD-L1 expression at the surface of tumor cells have been associated with increased response to anti-PD-1 therapies (Santabarbara G et al. Ann Transl Med. 2016;4:215; Borghaei H et al. N Engl J Med. 2015;373:1627-1639; Bra
Publikováno v:
Cancer Research. 81:PO-051
Tumor Treating Fields (TTFields) are a non-invasive, loco-regional antimitotic treatment modality, approved for the treatment of glioblastoma and malignant pleural mesothelioma. TTFields at a specific frequency (150-200 kHz) are delivered via arrays
Publikováno v:
Cancer Research. 81:PS14-10
Background: Male breast cancer has been less well studied due to the rarity of this condition compared with female breast cancer. Men have traditionally presented at later stages than women, leading to disparities in outcomes. Our aim was to identify