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Autor:
Michaela Lang, Rayko Evstatiev, Azra Kurtovic, Christoph Gasche, Ildiko Mesteri, Kyle Dammann, Vineeta Khare, Felix Harpain
Publikováno v:
Cancer prevention research (Philadelphia, Pa.). 8(11)
p21-activated kinase 1 (PAK1) is a serine/threonine kinase that is overexpressed in colorectal cancer. PAK1 is a target of mesalamine [5-aminosylicylic acid (5-ASA)], a common drug for the treatment of ulcerative colitis with prospective chemoprevent