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Autor:
Carole M. Lindsay, Kathleen Coard, Norma McFarlane-Anderson, Marshall K. Tulloch-Reid, Franklyn I. Bennett, Garrett Smith, Maria D. Jackson, William Aiken
Publikováno v:
Cancer Medicine
Circulating 25-hydroxyvitamin D [25(OH)D] concentrations have been associated with both higher and lower risk of prostate cancer (PCa), whereas elevated levels of circulating calcium has been related to higher risks. However, there are few studies th
Autor:
Kristina S Chen, Vahakn B. Shahinian, Sally W. Wade, Jane M Quigley, Jorge Arellano, David Quach, Alexander Liede, Rohini K. Hernandez, Melissa Pirolli
Publikováno v:
Cancer Medicine
The renal status of patients with bone metastases secondary to solid tumors and their treatment with nephrotoxic agents is not well characterized. This retrospective study analyzed electronic medical records data from US-based oncology clinics to ide
Publikováno v:
Cancer Medicine
Patients with nonresectable metastatic neuroendocrine tumors (NETs) experience symptoms of hormone hypersecretion including diarrhea, flushing, and bronchoconstriction, which can interfere with quality of life [Anthony and Vinik (2011) Pancreas, 40:9
Autor:
Chihaya Hinohara, Teruki Hagiwara, Yuki I. Kawamura, Oki Miyake, Toshio Shimizu, Miwa Tamura-Nakano, Takuhito Sezaki, Takeshi Otsubo, Taeko Dohi, Kazuhiko Yamada
Publikováno v:
Cancer Medicine
Periplakin (PPL), a member of the plakin family of proteins that localizes to desmosomes and intermediate filaments, is downregulated in human esophageal squamous cell carcinoma (ESCC). Little is known, however, about the molecular mechanism underlyi
Autor:
Mari Nishio, Nobuhisa Takase, Soken Utsunomiya, Hiroshi Yokozaki, Naoki Urakawa, Takahide Komori, Yu-ichiro Koma, Yoshihiro Kakeji, Hiroaki Akiyama, Manabu Shigeoka
Publikováno v:
Cancer Medicine
Tumor-associated macrophages (TAMs) are known to be involved in the progression of various human malignancies. We previously demonstrated that CD204 was a useful marker for TAMs contributing to the angiogenesis, progression, and prognosis of human es
Autor:
Dennis C. Shrieve, Kenneth M. Boucher, Li Ming Christine Fang, Leechuan Andy Chen, Luke O. Buchmann, Ying J. Hitchcock, Kenneth F. Grossmann, Jason P. Hunt, Christopher J. Anker
Publikováno v:
Cancer Medicine
Curative treatment for base-of-tongue squamous cell carcinoma (BOT SCC) has evolved over time; however, comparative outcomes analysis for various treatment strategies is lacking. The authors reviewed the evolution of treatment modality and radiothera
Autor:
Joyce Steinberg, Rene Gonzalez, Fei Jie, Bruce G. Redman, Ragini R. Kudchadkar, Bartosz Chmielowski, Caroline Chen, Anne Keating, Jeffrey S. Weber, Scott Ernst
Publikováno v:
Cancer Medicine
Survivin is a microtubule-associated protein believed to be involved in preserving cell viability and regulating tumor cell mitosis, and it is overexpressed in many primary tumor types, including melanoma. YM155 is a first-in-class survivin suppressa
Autor:
Victoria L. Bae-Jump, Megan Difurio, Paola A. Gehrig, K.M. Schuler, Liza Makowski, Brante P. Sampey, Brooke S. Rambally
Publikováno v:
Cancer Medicine
We conducted a preoperative window study of metformin in endometrial cancer (EC) patients and evaluated its antiproliferative, molecular and metabolic effects. Twenty obese women with endometrioid EC were treated with metformin (850 mg) daily for up
Autor:
Åsa Rangert Derolf, Tobias Svensson, Sigurdur Y. Kristinsson, Anders Ekbom, Ebba K. Lindqvist, Malin Hultcrantz, Magnus Björkholm, Fredrik Granath
Publikováno v:
Cancer Medicine
Solid tumors are associated with an increased risk of suicide, however, there is limited detailed information on the risk of suicide in patients with hematological malignancies. Therefore, we conducted a population-based study including 47,220 patien
Autor:
Yukinori Takenaka, Atsushi Hanamoto, Yuji Seo, Mitsuaki Tatsumi, Yoshifumi Yamamoto, Jun Hatazawa, Kazuhiko Ogawa, Toshimitsu Hamasaki, Toshimichi Yasui, Fumiaki Isohashi, Hidenori Inohara, Susumu Nakahara
Publikováno v:
Cancer Medicine
It is not well established whether pretreatment (18) F-FDG PET/CT can predict local response of head and neck squamous cell carcinoma (HNSCC) to chemoradiotherapy (CRT). We examined 118 patients: 11 with nasopharyngeal cancer (NPC), 30 with oropharyn