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Autor:
Sabine Oskar, Tari A. King, Bridget A. Oppong, Lindsay A. Pharmer, Sujata Patil, Michelle Stempel, Anne Eaton
Publikováno v:
Cancer Medicine
Observational data suggest that metformin use decreases breast cancer (BC) incidence in women with diabetes; the impact of metformin on BC outcomes in this population is less clear. The purpose of this analysis was to explore whether metformin use in
Autor:
Eric C. Leuthardt, Gene H. Barnett, Alireza M. Mohammadi, Stephen B. Tatter, Jason L. Schroeder, Ammar H. Hawasli, Paul Elson, Adrian W. Laxton, Analiz Rodriguez
Publikováno v:
Cancer Medicine
Surgical extent-of-resection has been shown to have an impact on high-grade glioma (HGG) outcomes; however, complete resection is rarely achievable in difficult-to-access (DTA) tumors. Controlled thermal damage to the tumor may have the same impact i
Autor:
Maria Ciccone, Massimo Negrini, Antonio Cuneo, Giulia Daghia, Elena Saccenti, Gian Matteo Rigolin, Francesco Cavazzini, Olga Sofritti
Publikováno v:
Cancer Medicine
Treatment of chronic lymphocytic leukemia (CLL) has dramatically changed over the last years, with significant improvement in overall survival (OS) and increased efficacy in genetically defined "high-risk" disease. Besides prospective clinical trials
Autor:
Noora Andersson, Ralf Bützow, Anniina Färkkilä, Mikko Anttonen, Arto Leminen, Markku Heikinheimo, Leila Unkila-Kallio
Publikováno v:
Cancer Medicine
Granulosa cell tumors (GCTs) carry a risk of recurrence also at an early stage, but reliable prognostic factors are lacking. We assessed clinicopathological prognostic factors and the prognostic roles of the human epidermal growth factor receptors (H
Autor:
Jingqin Luo, Daniel Morgensztern, Aaron D. Schenone, Douglas Adkins, Brian A. Van Tine, Luke Montgomery
Publikováno v:
Cancer Medicine
As adjuvant chemotherapy (AC) for soft tissue sarcomas is controversial, we performed a retrospective analysis of patients seen at Washington University in St. Louis to evaluate whether it benefited our patient population. Patients were risk-assessed
Autor:
Allan Hackshaw, Siow Ming Lee
Publikováno v:
Cancer Medicine
There are few predictive biomarkers for antiangiogenic trials in lung cancer. We examine a potential treatment strategy in which a patient group is enriched using both histology and an early assessment of response during standard chemotherapy, and wh