Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ena Wang"'
Autor:
Willem W. Overwijk, Patrick Hwu, Francesco M. Marincola, Geok Choo Sim, Caitlin Creasy, Laszlo Radvanyi, Chengwen Liu, Elizabeth A. Grimm, Hui Liu, Zhimin Dai, Ena Wang, Jason Roszik
Publikováno v:
Cancer Immunology Research. 4:983-994
Clinical responses to high-dose IL2 therapy are limited due to selective expansion of CD4+CD25+Foxp3+ T-regulatory cells (Treg), especially ICOS+ Tregs, rather than natural killer (NK) cells and effector T cells. These ICOS+ Tregs are highly suppress
Autor:
Marcus Bosenberg, Zulmarie Franco, Rahul Roychoudhuri, Liqiang Xi, Gautam U. Mehta, Hui Liu, Nicolas Acquavella, David Clever, Joseph G. Crompton, David F. Stroncek, Douglas C. Palmer, Mark Raffeld, James J. Morrow, Ena Wang, Christopher A. Klebanoff, Luca Gattinoni, Ken-ichi Hanada, Chyi-Chia Richard Lee, Alena Gros, Yun Ji, Zhiya Yu, Holger Pflicke, Melody E. Roelke-Parker, Madhusudhanan Sukumar, Ian S. Goldlust, Francesco M. Marincola, Nicholas P. Restifo
Publikováno v:
Cancer immunology research. 3(1)
Both targeted inhibition of oncogenic driver mutations and immune-based therapies show efficacy in treatment of patients with metastatic cancer, but responses can be either short lived or incompletely effective. Oncogene inhibition can augment the ef