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pro vyhledávání: '"Ena Wang"'
Autor:
Willem W. Overwijk, Patrick Hwu, Francesco M. Marincola, Geok Choo Sim, Caitlin Creasy, Laszlo Radvanyi, Chengwen Liu, Elizabeth A. Grimm, Hui Liu, Zhimin Dai, Ena Wang, Jason Roszik
Publikováno v:
Cancer Immunology Research. 4:983-994
Clinical responses to high-dose IL2 therapy are limited due to selective expansion of CD4+CD25+Foxp3+ T-regulatory cells (Treg), especially ICOS+ Tregs, rather than natural killer (NK) cells and effector T cells. These ICOS+ Tregs are highly suppress