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Publikováno v:
Cancer Immunology Research. 1:309-319
Although antitumor activity of herpes simplex virus 1 (HSV-1) ICP0 null oncolytic vectors has been validated in murine breast cancer models, oncolytic virus treatment alone is insufficient to break immune tolerance. Thus, we investigated enhancing ef
Autor:
Reiner Strick
Publikováno v:
Cancer Immunology Research. 5:IA02-IA02
Endogenous retroviruses (ERVs) are derived from past exogenous retroviral infections of germ cells, which integrated into the genome of mammals and are inherited in a Mendelian manner. ERVs belong to the class of retro-elements possessing three main
Autor:
Pu Gao
Publikováno v:
Cancer Immunology Research. 4:B145-B145
Cyclic GMP-AMP synthase (cGAS) plays a central role in sensing aberrantly localized cytoplasmic dsDNA. Upon binding dsDNA, cGAS synthesizes the cyclic dinucleotide cGAMP, which acts as a second messenger to initiate a signaling pathway for the induct
Autor:
Young-Min Kim, Sae Won Kim, Young Chul Sung, Ji-Hae Kim, Seung Won Lee, Han Wook Park, Seung-Woo Lee, Hyekang Kim
Publikováno v:
Cancer Immunology Research. 4:B012-B012
Most targeted therapy drugs block the growth of cancer cells by targeting specific molecules needed for tumor growth. Among targeted therapy drugs, cetuximab, the monoclonal antibody which binds to epidermal growth factor receptor (EGFR) and inhibits
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