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Autor:
Willemijn van den Ancker, Hetty J. Bontkes, Tanja D. de Gruijl, Jurjen M. Ruben, Erik Hooijberg, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht, Theresia M. Westers
Publikováno v:
Ruben, J M, van den Ancker, W, Bontkes, H J, Westers, T M, Hooijberg, E, Ossenkoppele, G J, de Gruijl, T D & van de Loosdrecht, A A 2014, ' Apoptotic blebs from leukemic cells as a preferred source of tumor-associated antigen for dendritic cell-based vaccines ', Cancer Immunology and Immunotherapy, vol. 63, no. 4, pp. 335-345 . https://doi.org/10.1007/s00262-013-1515-6
Cancer Immunology and Immunotherapy, 63(4), 335-345. Springer Science and Business Media Deutschland GmbH
Cancer Immunology and Immunotherapy, 63(4), 335-345. Springer Science and Business Media Deutschland GmbH
Since few leukemia-associated antigens (LAA) are characterized for acute myeloid leukemia (AML), apoptotic tumor cells constitute an attractive LAA source for DC-based vaccines, as they contain both characterized and unknown LAA. However, loading DC