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pro vyhledávání: '"Gregory P. Adams"'
Autor:
Barbara Burtness, Linara Gabitova, Tetyana V. Bagnyukova, Gregory P. Adams, Kathy Q. Cai, Hanqing Liu, Yan Zhou, Ilya G. Serebriiskii, Anna Sukhanova, Gail E. Herman, Lisa E. Kratz, David Cunningham, Igor Astsaturov, Ranee Mehra, Richard I. Kelley, Diana Restifo, Erica A. Golemis, Andrey Gorin, Brian L. Egleston, Hui Zheng, Louis M. Weiner, Dong-Hua Yang, Anna S. Nikonova, Andres J. Klein-Szanto
Publikováno v:
Cancer Discovery. 3:96-111
Persistent signaling by the oncogenic EGF receptor (EGFR) is a major source of cancer resistance to EGFR targeting. We established that inactivation of 2 sterol biosynthesis pathway genes, SC4MOL (sterol C4-methyl oxidase–like) and its partner, NSD