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Autor:
Darell D. Bigner, Robert C. Moschel, Gerald E. Archer, Shekar N. Kurpad, Roger E. McLendon, Henry S. Friedman, M. Eileen Dolan, Anthony E. Pegg
Publikováno v:
Cancer chemotherapy and pharmacology. 39(4)
The prognosis for patients with malignant gliomas continues to be dismal. The high degree of resistance of gliomas to nitrosourea-based chemotherapy is one major factor in poor treatment outcome. The identification of O6-alkylguanine-DNA alkyltransfe